High-entropy alloys (HEAs), also known as multicomponent or multi-principal element (MPEAs), differ from traditional alloys, which are usually based only on one principal element, in that they fabricated five more elements large percentages related to each other, the range of 5%–35%. Despite outstanding characteristics HEAs, a properly selected design, many such coated with advanced composites ...

Chemical genetics is a powerful scientific strategy that utilizes small bioactive molecules as experimental tools to unravel biological processes. Bioactive compounds occurring in nature represent an enormous diversity of structures that can be used to dissect functions of biological systems. Once the bioactivity of a natural or synthetic compound has been critically evaluated the challenge rem...

background: woodfordia fruticosa is used traditionally as antidysenteric compound for fodder animals. stem and flower extracts are previously flourished for their antibacterial activity. leaves are also equally important, which are preliminary screened for their bioactive components in present study. objective: evaluation of antibacterial activity of leaves of w. fruticosa and detection of thei...

background and objectives: in the present study, isolation of streptomyces associated with marine sponges and its bioactive potential against fish and shellfish pathogens were assessed. the streptomyces sp. were isolated from the marine sponges namely callyspongia diffusa, mycale mytilorum, tedania anhelans and dysidea fragilis collected from vizhinjam port, situated in the south-west coast of ...

generation neural stem cells from neurosphere–derived bone marrow stem cells using bioactive substance atc. bone marrow cells (bmscs) were isolated from rat. bmscs cultured by dmem/f12 medium supplemented with 10% fetal bovine serum. these cells evaluated by specific markers of bmscs such as bioactive substance atc, b27. then bmscs differentionated in to neurosphere and divided in two groups wh...

in this study the bacterial growth inhibitory activity of peptide fragments produced from goat’s milk whey proteins by enzymatic hydrolysis using trypsin, ficin and a combination of both was investigated. goat’s milk whey proteins were isolated and subjected to enzymatic hydrolysis and peptides were purified by ultrafiltration followed by reverse-phase high-performance liquid chromatography (rp...

liposomes have attracted great interest as efficient carriers for nutrients, drugs and other bioactive agents as well as ideal models for biological membranes. this article intends to provide an overview of liposomes and nanoliposomes definition as well as their properties and preparation methods. also it elaborates on various applications of nanoliposomes in nanotherapy including diagnostics, ...

screening of microorganisms for the production of novel antibiotics has been intensivelypursued for many years by scientists. actinomycetes have the capability to synthesize manydifferent antibiotics. a total of 69 actinomycete isolates were recovered from soil samplescollected from alborz province. selected colonies (rough, chalky) of actinomycetes werepurified. all screened isolates were iden...

The cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-clinical applications. This study was designed to evaluate and compare the cytotoxixity of two forms of bioactive glasses:nanopowder:andmicropowder. Human HGF1-PI53 gingival fibroblast cells were used to evaluate the cytotoxicity of 0.5, 1, 1.5, 2, 5, 10, 15 and 20 mg/mL concentrations of the two bioactive...