نتایج جستجو برای: binding variable
تعداد نتایج: 670766 فیلتر نتایج به سال:
Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.
We have created mouse-human antibody molecules of defined antigen-binding specificity by taking the variable region genes of a mouse antibody-producing myeloma cell line with known antigen-binding specificity and joining them to human immunoglobulin constant region genes using recombinant DNA techniques. Chimeric genes were constructed that utilized the rearranged and expressed antigen-binding ...
This thesis argues that principles of economy play an important role in determining the form of linguistic structures at the interface with the semantic component. The argument comes in the form of a variety of proposals regarding specific mechanisms that are active at this interface. Specifically, I suggest that Economy plays a role in determining relative scope, variable binding, and the form...
Drosophila Dscam encodes a vast family of immunoglobulin (Ig)-containing proteins that exhibit isoform-specific homophilic binding. This diversity is essential for cell recognition events required for wiring the brain. Each isoform binds to itself but rarely to other isoforms. Specificity is determined by "matching" of three variable Ig domains within an approximately 220 kD ectodomain. Here, w...
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