By proposing a predictive method with no adjustable parameter and by using infinite dilution activity coefficients of components in binary mixtures obtained from UNIFAC model, the binary interaction parameters (k12) in van der Waals mixing rule (vdWMR) and Orbey-Sandler mixing rule (OSMR) have been evaluated. The predicted binary interaction parameters are used in Peng-Robinson-S...

Clostridium difficile binary toxin (CDT) is an actin-specific ADP-ribosyltransferase that is produced by various C. difficile isolates, including the "hypervirulent" NAP1/027 epidemic strains. In contrast to the two major toxins from C. difficile, toxin A and toxin B, little is known about the role of CDT in virulence or how C. difficile regulates its production. In this study we have shown tha...

the srk two-parameter cubic equation of state has been used for the calculation of the equilibrium constant using the liquid and vapor fugacity coefficients for three binary mixtures. dew and bubble points have been determined using the equilibrium constants and the phase envelope has been plotted showing dearly that retrograde condenstaion occurs. the following percent deviations have been obt...

Motivated by an empirical analysis of ecological momentary assessment data (EMA) collected in a smoking cessation study, we propose a joint modeling technique for estimating the time-varying association between two intensively measured longitudinal responses: a continuous one and a binary one. A major challenge in joint modeling these responses is the lack of a multivariate distribution. We sug...

longitudinal  study  plays  an  important  role  in  the  epidemiological,  clinical,  and  social  science studies. in these kinds of studies, every individual is observed frequently during a period of time. the statistical analysis of longitudinal presents special opportunities  and challenges. the repeated outcomes for one individual tend to be correlated among themselves also one of the pro...

the concept of  -semihypergroups is a generalization of semigroups, a generalization of semihypergroups and a generalization of  -semigroups. in this paper, we study the concept of semiprime ideals in a  -semihypergroup and prove some results. also, we introduce the notion of  -hypergroups and closed  -subhypergroups. finally, we study the concept of  -semihypergroups associated to binary...

a capillary electrophoresis method was used for assay of some degradation products of carvedilol. the optimized parameters were as; running buffer 80 mm acetate dissolved in methanol/ethanol mixture (65:35 v/v), applied voltage of 19 kv, temperature is 20 ºc and the wavelength range of 200-350 nm. the results indicate that the proposed ce method could effectively separate carvedilol from its de...

Background: Alcohol dependence (AD) is a major reason for morbidity and visits to emergency medical settings. However, the detection of AD is often difficult or overlooked. This study aimed to develop a brief screening questionnaire in Hindi language for detection of AD in an emergency medical setting. Methods:  The authors in consultation devised a set of questions related to AD in the Hindi l...

We study the response of an autoregulated gene to a range of concentrations of signal molecules. We show that transcriptional leakage and noise due to translational bursting have the opposite effects. In a positively autoregulated gene, increasing the noise converts the response from graded to binary, while increasing the leakage converts the response from binary to graded. Our findings support...