We present a new GCD algorithm for two integers that combines both the Euclidean and the binary gcd approaches. We give its worst case time analysis and prove that its bit-time complexity is still O(n) for two n-bit integers. However, our preliminar experiments show that it is very fast for small integers. A parallel version of this algorithm matches the best presently known time complexity, na...

The present work was carried out to assess the value of adding water insoluble polymer meloxicam amorphous solid formulation (ASD). Meloxicam mixed with polyvinylpyrrolidone (PVP) (1:1 ratio) as a binary mixture and PVP ethyl cellulose (1:1:1 ternary mixture. Solvent evaporation method used prepare ASD formulations. differential scanning calorimetry, powder X-Ray diffraction, Cambridge Structur...

Changes in the (31)P NMR chemical shift of tri-n-butylphosphine oxide have been measured as function of solvent composition in a number of binary solvent mixtures. The data were analysed using a model that separates the contributions of specific H-bond interactions with the first solvation shell and the non-specific effects of the bulk solvent on the chemical shift. This allowed measurement of ...

Some drugs have low bioavailability due to their poor aqueous solubility and/or slowdissolution rate in biological fluids. Stiripentol (STP) is a novel anticonvulsant drug that isstructurally unrelated to the currently available antiepileptics. It has poor aqueous solubilityand its solubility has to be enhanced accordingly. Polyethyleneglycol 6000 (PEG-6000) iscommonly utilized as a hydrophilic...

Inclusion of low-resolution data in macromolecular crystallography requires a model for the bulk solvent. Previous methods have used a binary mask to accomplish this, which has proven to be very effective, but the mask is discontinuous at the solute-solvent boundary (i.e. the mask value jumps from zero to one) and is not differentiable with respect to atomic parameters. Here, two algorithms are...

Kinetics of the neutral hydrolysis of 4-nitrophenyl chloroacetate was investigated in water and in the presence of 1 mol % of ethanol, propanol, and -butyl n alcohol without sonication and under ultrasound at 25 kHz. Similarly, the kinetics of the acid-catalysed hydrolysis of -propyl n acetate in ethanol–water binary solutions was investigated without sonication and under ultrasound at 22 kHz. ...

Recommended Reference Value Standards based on the potassium hydrogenphthalate buffer at various temperatures are reported for pH measurements in various binary solvent mixtures of water with eight organic solvents: methanol, ethanol, 2-propanol, 1,2-ethanediol, 2-methoxyethanol (“methylcellosolve”), acetonitrile, 1,4-dioxane, and dimethylsulphoxide, together with Reference Value Standards base...

This article reviews the synergistic effects of engineering binary solvents on crystallization, morphology and charge transport organic semiconductors.