Multimodal imaging is a highly desirable biomedical application since it can provide complementary information from each imaging modality. We propose a protein engineering-based strategy for the construction of a bimodal probe for fluorescence and magnetic resonance imaging. A recombinant protein was generated by the fusion of a supercharged green fluorescence protein (GFP36+) with a lanthanide...

Magnetic resonance (MR) diffusion imaging provides a valuable tool used for inferring structural anisotropy of brain white matter connectivity from diffusion tensor imaging. Recently, several high angular resolution diffusion models were introduced in order to overcome the inadequacy of the tensor model for describing fibre crossing within a single voxel. Among them, q-ball imaging (QBI), inher...

Lung adenocarcinoma is the most common type of lung cancer. A close monitor of in vivo tumor development may help to better understand the pathogenesis and pathological processes of this disease. A bimodal imaging strategy has been developed, which is a very important tool to investigate the growth and metastasis of lung adenocarcinoma. In the present study, we used a combined labeling strategy...

UNLABELLED BACKGROUND Bimodal molecular imaging with fluorescence diffuse optical tomography (fDOT) and positron emission tomography (PET) has the capacity to provide multiple molecular information of mouse tumors. The objective of the present study is to co-register fDOT and PET molecular images of tumors in mice automatically. METHODS The coordinates of bimodal fiducial markers (FM) in r...

Hollow core, mesoporous shell carbon nanospheres (HCMSs) with large bimodal mesopores (6.4 and 3.1 nm) and high surface area (1704 m(2) g(-1)) have been synthesized by a triconstituent surface co-assembly of monodisperse silica nanospheres method. The resulted HCMS show a high specific capacity of 251 F g(-1) at 50 mV s(-1) in 2 M H(2)SO(4) and long cyclic life.

We propose an implementation of a source of strongly sub-poissonian light in a system consisting of a quantum dot coupled to both modes of a lossy bimodal optical cavity. When one mode of the cavity is resonantly driven with coherent light, the system will act as an efficient single photon filter, and the transmitted light will have a strongly sub-poissonian character. In addition to numerical ...

While infrared upconversion imaging using halide nanoparticles are so common the search for a very efficient halide free upconverting phosphors is still lacking. In this article we report Gd2O2S:Yb/Er,YbHo,YbTm systems as a very efficient alternative phosphors that show upconversion efficiency comparable or even higher than existing halide phosphors. While the majority of rare earth dopants pro...