biliary papillomatosis is a disorder characterized by numerous adenomatous polyps of variable distribution and extent in intrahepatic bile ducts. it should be considered as a premalignant condition because a high proportion of the lesions undergo malignant transformation. in this report, we present a patient with abdominal pain and jaundice. according to his presenting signs and symptoms, ercp ...

Correspondence and reprint requests to: Dr. Rona E. Cheifetz, c/o Department of Surgery, Faculty of Medicine, 910 West 10th Ave., 3rd Floor, Vancouver BC V5Z 4E3 OBJECTIVE: To adapt an animal model of benign bile-duct stricture, sclerosing cholangitis and cholangiocarcinoma in order to determine if the expression of epidermal growth factor receptor (EGFr) could be used to differentiate these le...

PURPOSE Reversible obstructive jaundice models have some limiting features, including the need for a second anaesthesia, re-laparotomy and surgical intervention after common bile duct ligation. The present study investigates the feasibility of a new application that can eliminate these limitations. Rapidly absorbable suture materials were used for ligation; therefore, spontaneous biliary decomp...

Background: In some disorders such as diabetes mellitus patients can display depressive symptoms. Metformin is among the first-line treatments for management of the type 2 diabetes mellitus which may have some anti-depressant effect. Objective: Current investigation was performed to examine the anti-depressant effects of metformin and the involvement of nitric oxide (NO) in this way, in an expe...

INTRODUCTION Bile duct injury is a severe and potentially life-threatening complication of laparoscopic cholecystectomy. Several series have described a 0.5% to 0.6% incidence of bile duct injury during laparoscopic cholecystectomy. The aim of this study was to analyze the presentation, characteristics, related investigation, and treatment results of major bile duct injuries after laparoscopic ...

aim : to assess the complications of bile duct injury in laparoscopic cholecystectomy in loghman medical center, tehran. background : the incidence of complications of laparoscopic cholecystectomy has increased dramatically since the introduction and widespread use of laparoscopic cholecystectomy.  patients and methods : from january 1998 to january 2002, a total of 155 laparoscopic cholecystec...

In pediatric practice it was not infrequent to meet with a difficulty in etiological diagnosis for neonatal jaundice. For example, both neonatal hepatitis and atresia of the bile duct would present similar clinical and laboratory findings of "obstructive jaundice", and while an early surgical treatment is recommended for the cases with atresia of the bile duct, the therapy for those of neonatal...

Objective(s): Cirrhotic cardiomyopathy refers to cardiac muscle dysfunction caused by liver cirrhosis. Seemingly, free radicals and inflammatory factors play a critical role in the pathophysiology of cardiomyopathy. Curcumin has the anti-inflammatory, antioxidant, and anticancer properties . However, the therapeutic indications of this compound are limited due to its low absorption, rapid metab...