نتایج جستجو برای: benzyl pyridin 2 yl methylcarbamodithioate

تعداد نتایج: 2534431  

Journal: :Acta Crystallographica Section E Structure Reports Online 2011

Journal: :Acta Crystallographica Section E Structure Reports Online 2013

Journal: :Acta Crystallographica Section E Structure Reports Online 2013

2013
N. Sree Lakshmana Rao Mandava V. Basaveswara Rao

Encouraged by the biological activities associated with chalcones and furo[3,2-c]pyridine, the present paper describes the synthesis, spectroscopic identification and antibacterial activity of furo[3,2-c]pyridine chalcone derivatives i.e. 8a-8g in a few high yielding steps from commercially available 2-Furaldehyde. Claisen Schmidt condensation of aldehyde 7 with various acetophenones (R = a-g) ...

2010
Dan Niculescu-Duvaz Ion Niculescu-Duvaz Bart M.J.M. Suijkerbuijk Delphine Ménard Alfonso Zambon Arnaud Nourry Lawrence Davies Helen A. Manne Frank Friedlos Lesley Ogilvie Douglas Hedley Andrew K. Takle David M. Wilson Jean-Francois Pons Tom Coulter Ruth Kirk Neus Cantarino Steven Whittaker Richard Marais Caroline J. Springer

V-RAF murine sarcoma viral oncogene homolog B1 (BRAF) is a serine/threonine-specific protein kinase that is mutated with high frequency in cutaneous melanoma, and many other cancers. Inhibition of mutant BRAF is an attractive therapeutic approach for the treatment of melanoma. A triarylimidazole BRAF inhibitor bearing a phenylpyrazole group (dimethyl-[2-(4-{5-[4-(1H-pyrazol-3-yl)-phenyl]-4-pyri...

Journal: :Acta Crystallographica Section E Structure Reports Online 2012

2012
Susanne Wöhlert Christian Näther

The asymmetric unit of the title compound, [Co(NCS)(2)(C(13)H(14)N(2))(CH(3)OH)(2)], consists of one cobalt(II) cation located on a center of inversion, one half of a 1,3-bis-(pyridin-4-yl)propane ligand located on a twofold rotation axis, as well as one thio-cyanate anion and one methanol mol-ecule in general positions. The cobalt(II) cation is coordinated by two terminal N-bonded thio-cyanate...

Journal: :Acta Crystallographica Section E Structure Reports Online 2014

Kiran Gadekar, Vikas Gopalrao Rajurkar Vinayak K Deshmukh

Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. In line with these developments the synthesis of N-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4H-1...

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