Catechols are components of many metal-chelating compounds, including siderophores that are naturally occurring iron(III) chelators excreted by microorganisms. Catechol derivatives are poorly soluble in organic media and the synthesis of catechol-containing molecules requires the use of protected catechol precursors with improved organic solubility. We therefore developed 2,2-diphenyl-benzo[1,3...

The structure of 2-[(4-chlorophenylazo) cyanomethyl] benzoxazole, C15H9ClN4O (I), has triclinic ([Formula: see text]) symmetry. The structure displays N-H ⋯ N hydrogen bonding. The structure of 2-[(arylidene) cyanomethyl] benzoxazoles, C17H10N2O3 (II), has triclinic ([Formula: see text]) symmetry. The structure displays C-H ⋯ N, C-H ⋯ C hydrogen bonding. In (I), the chlorophenyl and benzoxazole...

Unspecific peroxygenases (UPOs) enable oxyfunctionalizations of a broad substrate range with unparalleled activities. Tailoring these enzymes for chemo- and regioselective transformations represents grand challenge due to the difficulties in their heterologous productions. Herein, we performed protein engineering Saccharomyces cerevisiae using MthUPO from Myceliophthora thermophila. More than 5...

Twelve methylenedioxy-containing compounds including piperine and 10 piperine-like synthetic compounds were assessed to determine their antifungal and antiaflatoxigenic activities against Aspergillus flavus ATCC 22546 in terms of their structure-activity relationships. Piperonal and 1,3-benzodioxole had inhibitory effects against A. flavus mycelial growth and aflatoxin B₁ production up to a con...

Dried and ground leaves of Crithmum maritimum were used as a matrix for supercritical extraction of volatile oil with CO2. Operative conditions were: extractor, 90 bar and 50 °C for 240 min; first separator, 90 bar and –10°C; second separator, 15 bar and 15 °C. GC/MS analysis of the leaves volatile oil revealed that it mainly consisted of: para-cymene, βphellandrene, γ-terpinene, thymol methyl ...

A series of cyclic acetals were investigated with regard to their ability to function as coinitiators in free-radical photopolymerization induced by camphorquinone (CQ). Among these cyclic acetals, the reactivity of 2-hexyl-1,3-benzodioxole (HBDO) was the highest, according to the quantum yield of CQ. However, the most efficient coinitiator was l,3-benzodioxolane, which has a reactivity signifi...

THE TITLE COMPOUND (SYSTEMATIC NAME 4,7-methano-2,2'-spirobi-[1,3-benzodioxole]), C(14)H(14)O(4), is an asymmetric spiro ester of orthocarbonic acid and two diols, viz. the aromatic benzene-1,2-diol and the aliphatic vicinal norbornane-exo-cis-2,3-diol. The orthocarbonate mol-ecule is close to having non-crystallographic C(s) symmetry. The five-membered ring stemming from the aliphatic diol has...

In the title compound, C17H15N3O2, two independent mol-ecules (A and B) comprise the asymmetric unit. The major conformational difference arises in the relative orientation of the pyrazole ring amine and dioxole substituents which are anti in A and syn in B. The five-membered dioxole ring in each mol-ecule has an envelope conformation with the methyl-ene C atom as the flap. The mean plane throu...