Schiff base condensation of benzil bis(hydrazone) with formaldehyde, acetone and benzaldehyde and its nickel(II) complexes were synthesised. Preparation of the free ligands was accomplished by refluxing benzil with hydrazine derivatives in 1:10 mole ratios in ethylene glycol. The spectral characterisation of hydrazone based 14-membered octaaza macrocyclic complexes of nickel(II) was undertaken....

Flavonoids and other phenolic compounds were determined in 15 samples of propolis originating from China, from Brazil, and from Uruguay. A total of 24 compounds were identified using mainly HPLC and a few other analytical methods. The most abundant com­ pounds found were benzoic acid and benzaldehyde derivatives, flavones, flavonols. and flavanones. 80% of the samples contained at least 22 g/10...

The title compounds were prepared by brominating 1-acetylnaphthalene in chloroform followed by condensation with substituted benzaldehyde thiosemicarbazones using ethanol to get 4-naphthalen-1-yl-2-{2-[(substituted phenyl)methylidene]hydrazino}-1,3-thiazoles. These thiazole derivatives were then cyclized to title compounds by reacting with thiomalic acid in dioxane using ZnCl2. All the synthesi...

Flash vacuum pyrolysis (FVP) of 4-aryl-3-buten-2-ols [ArCH=CH-CH(CH3)OH, where Ar is phenyl, p-MeO, p-Me, p-Cl, p-NO2] gave the corresponding buta-1,3-dien-1-ylbenzene (ArCH=CH-CH=CH2, where Ar is Ph, p-MeO, p-Me, p-Cl, p-NO2) and 7-X-1,2-dihydronaphthalene derivatives (where X is H, MeO); FVP of 1-aryl-3-benzyloxy1-1-butenes and benzyl cinnamyl ethers [ArCH=CHCH(X)OCH2Ph, where Ar is phenyl, p...

An efficient and economical method was developed for the synthesis of 3-substituted indoles by one-pot three-component coupling reaction of a substituted or unsubstituted benzaldehyde, N-methylaniline, and indole or N-methylindole using Yb(OTf)(3)-SiO(2) as a catalyst. All the synthesized compounds were evaluated for inhibition of cell proliferation of human colon carcinoma (HT-29), human ovari...

The derivatives of fused pyrimidines are valued not only for their rich and varied chemistry, but also for many important biological properties [1 – 3]. Among them, the pyridodipyrimidines (PDP) have been shown to exhibit antibacterial and antiviral properties [4, 5] as well as NAD-type redox catalytic activity [6 – 10]. A few methods are reported in the literature for the preparation of pyrido...

In this study some new o-benzimidazol-2'-yl-benzamido-p'-benzamido-2-phenyl-4-substituted phenyl-5-oxo-Imidazolines 3a-3j were synthesized. To synthesized target molecules we used various substituted oxazolone derivatives, synthesized from substituted benzaldehyde with hippuric acid. Substituted oxazolones 2a-2j were reacted with carbohydrazide derivative of benzimidazole 1 in presence of pyrid...

Volatile compounds from the headspace gas of ten brands of the Japanese fish sauce ishiru were analyzed by GC-MS with a thermal-desorption cold-trap system. Many volatile peaks were detected and 51 compounds were identified. The major volatile compounds in ishiru included aldehydes (such as 2-methylpropanal, 2-methylbutanal, 3-methylbutanal, and benzaldehyde), nitrogen-containing compounds (suc...