STUDY DESIGN Retrospective review of a consecutive clinical series. OBJECTIVES To assess the efficacy and clinical value of cantilever bending technique as a technique for correcting large (> or =70 degrees ) and rigid (flexibility < or =30%) scoliosis. SUMMARY OF BACKGROUND DATA Scoliosis correction by current methods is a compromise between the rigidity of the deformity and corrective for...

It has been known since Maxwell that collections of particles interacting via central forces only become rigid above the isostatic threshold, where the constraints and internal degrees of freedom just balance [1,2]. However, such networks can be stabilized below this threshold by additional interactions [3–5]. Here we elucidate the relative roles of bending versus central force interactions in ...

(F-) actin or microtubules belong to the class of semi-flexible polymers. The biological function of these polymers requires considerable mechanical rigidity. For example, actin filaments are the main structural element of the cytoskeleton which gives the cell unique mechanical properties as it forms a network rigid enough to maintain the shape of the cell and to transmit forces, yet flexible e...

In vitro comparative testing of fracture fixation implants is limited by the highly variable material properties of cadaveric bone. Bone surrogate specimens are often employed to avoid this confounding variable. Although validated surrogate models of normal bone (NB) exist, no validated bone model simulating weak, osteoporotic bone (OPB) is available. This study presents an osteoporotic long-bo...

Measurements of the ultralow interfacial tension and surfactant film bending rigidity for micron-sized heptane droplets in bis(2-ethylhexyl) sodium sulfosuccinate−NaCl aqueous solutions were performed in a microfluidic device through the analysis of thermally driven droplet interface fluctuations. The Fourier spectrum of the stochastic droplet interface displacement was measured through bright-...

Biological membranes are involved in numerous intriguing biophysical and biological cellular phenomena of different length scales, ranging from nanoscale raft formation, vesiculation, to microscale shape transformations. With extended length and time scales as compared to atomistic simulations, solvent-free coarse-grained membrane models have been exploited in mesoscopic membrane simulations. I...

We study the pinning of a two-dimensional membrane to a patterned substrate within elastic theory both in the bending rigidity and in the strain-dominated regimes. We find that both the in-plane strains and the bending rigidity can lead to depinning. We show from energetic arguments that the system experiences a first-order phase transition between the attached configuration to a partially deta...

Objective This study was performed to investigate the effect of parathyroid hormone (PTH) on healing in osteoporotic fractures via a phospholipase C (PLC)-independent pathway and explore the mechanism of PTH-mediated bone formation. Methods Ninety-six 12-week-old C57BL/6J female mice underwent bilateral ovariectomy. One month later, the lower third of the femur was fractured and the mice were t...

A method has been proposed for developing structure-property relationships of nano-structured materials. This method serves as a link between computational chemistry and solid mechanics by substituting discrete molecular structures with equivalent-continuum models. It has been shown that this substitution may be accomplished by equating the molecular potential energy of a nano-structured materi...

A method has been proposed for developing structure-property relationships of nano-structured materials. This method serves as a link between computational chemistry and solid mechanics by substituting discrete molecular structures with equivalent-continuum models. It has been shown that this substitution may be accomplished by equating the molecular potential energy of a nano-structured materi...