نتایج جستجو برای: behavioral abnormalities

تعداد نتایج: 247477  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Wataru Kamitani Etsuro Ono Saori Yoshino Tsutomu Kobayashi Satoshi Taharaguchi Byeong-Jae Lee Makiko Yamashita Takeshi Kobayashi Minoru Okamoto Hiroyuki Taniyama Keizo Tomonaga Kazuyoshi Ikuta

One hypothesis for the etiology of behavioral disorders is that infection by a virus induces neuronal cell dysfunctions resulting in a wide range of behavioral abnormalities. However, a direct linkage between viral infections and neurobehavioral disturbances associated with human psychiatric disorders has not been identified. Here, we show that transgenic mice expressing the phosphoprotein (P) ...

Journal: :International Journal of Health Sciences (IJHS) 2023

Background: In this research, premenopausal women with HR-HPV infections and atypical cervical smears were compared by age. Materials method: 200 regularly screened between the ages of 36 60 had a smear HPV detection. Demographic, behavioral, medical data gathered telephone surveys. Descriptive analysis was used to look at connection aberrations Results: Age significantly decreased number cases...

Journal: :Developmental neuroscience 2011
Jose Luis Olmos-Serrano Joshua G Corbin Mark P Burns

Hyperactivity, hypersensitivity to auditory stimuli, and exaggerated fear are common behavioral abnormalities observed in individuals with fragile X syndrome (FXS), a neurodevelopmental disorder that is the most common genetic cause of autism. Evidence from studies of the Fmr1 knockout (KO) mouse model of FXS supports the notion that impaired GABAergic transmission in different brain regions su...

Journal: :PLoS ONE 2008
Yasuhide Iwata Katsuaki Suzuki Tomoyasu Wakuda Norihito Seki Ismail Thanseem Hideo Matsuzaki Takayoshi Mamiya Takatoshi Ueki Sumiko Mikawa Takeshi Sasaki Shiro Suda Shigeyuki Yamamoto Kenji J. Tsuchiya Genichi Sugihara Kazuhiko Nakamura Kohji Sato Nori Takei Kenji Hashimoto Norio Mori

BACKGROUND Epidemiological studies suggest that radiation exposure may be a potential risk factor for schizophrenia in adult humans. Here, we investigated whether adult irradiation in rats caused behavioral abnormalities relevant to schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS A total dose of 15-Gy irradiation in six fractionations during 3 weeks was exposed to the forebrain including the su...

2015
Kazue Muraki Kenji Tanigaki

Schizophrenia is a complex mental disorder that displays behavioral deficits such as decreased sensory gating, reduced social interaction and working memory deficits. The neurodevelopmental model is one of the widely accepted hypotheses of the etiology of schizophrenia. Subtle developmental abnormalities of the brain which stated long before the onset of clinical symptoms are thought to lead to...

2015
Manpreet Kaur Shilpi Sachdeva Onkar Bedi Tavleen Kaur Puneet Kumar

BACKGROUND Diabetic nephropathy (DN) is one of the complex complications of Diabetes Mellitus (DM). The present study has been designed to examine protective role of hydrogen Sulphide (H2S) donor against streptozotocin (STZ) -induced behavioral, oxidative abnormalities and its DN like symptoms in rats. METHODS For the induction of DN single intraperitoneal administration of STZ (45 mg/kg) was...

Journal: :Molecular syndromology 2012
D Horn

Very recently, FOXP1 deficiency was shown to result in a phenotype of intellectual disability with significant speech and language impairment. Behavioral abnormalities should be considered as part of the clinical spectrum. Mild craniofacial abnormalities found in half of the described patients expand the clinical spectrum associated with FOXP1 mutations.

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