The repair of bone defects is of particular interest for orthopedic, oral, maxillofacial, and dental surgery. Bone loss requiring reconstruction is conventionally addressed through bone grafting. Depending on the size and the location of the defect, this method has limits and risks. Biomaterials can offer an alternative and have features supporting bone repair. Here, we propose to evaluate the ...

Purpose: The aim of this work was to prepare nimodipine-loaded alginate-chitosan beads for sustained drug release. Methods: Nimodipine-loaded alginate-chitosan beads were prepared by ionic gelation method using various combinations of chitosan and Ca 2+ as cations and alginate as anion. The swelling ability and in vitro drug release characteristics of the beads were studied at pH 1.2 and 6.8. I...

Four hydrophilic polymers in the form of beads - chitosan, alginate, alginate/polyvinyl alcohol (PVA), and chitosan-coated alginate - were used as supports for lipase immobilisation. Hydrogel beads were characterised by bead-size-distribution estimation, surface morphology studies, and polymer interactions assessment. Matrix performances - loading efficiency, immobilisation yield, enzyme activi...

This work aimed to test the new Mag-Bind® TotalPure magnetic beads in construction of a genomic library corn and sugarcane endophytes. The technique Next-Generation Sequencing (NGS) is very expensive for that, one most reagents are magnetics that serve purify amplified DNA separate by size depending on their proportion, as shown Illumina protocol. We observed use these beads, which five times c...

The use of fluorescence calibration beads has been the hallmark of quantitative flow cytometry. It has enabled the direct comparison of interlaboratory data as well as quality control in clinical flow cytometry. In this article, we describe a simple method for producing color-generalizable calibration beads based on streptavidin functionalized quantum dots. Based on their broad absorption spect...

High molecular weight alginate beads with 59% mannuronic acid content or 68% guluronic acid were prepared using a droplet generator and crosslinked in calcium chloride. The alginate beads were compared to current embolisation microspheres for compressibility and monitored over 12 weeks for size and weight change at 37 degrees C in low volumes of ringers solutions. A sheep uterine model was used...

While granular segregation in partially filled containers has been studied extensively, dynamics densely spheres is not fully understood. Here, surface band and convection are reported a rotating sphere of highly compacted glass beads. Distinct from the Rayleigh–Bénard convection, butterfly shaped structure with vortexes alternating layers small/large beads, which stable independent size. Two c...

Chitosan with excellent biodegradable and biocompatible characteristics has received attention as an oral drug delivery vehicle for controlled-release formulations. In this study an enteric-coated capsule containing theophylline-chitosan beads based on 23 factorial designs was prepared as a colon drug delivery system. The theophylline-chitosan gel beads were formulated by adding the drug-contai...

The binding and phagocytosis of fibronectin (pFN)-coated latex beads by baby hamster kidney (BHK) cells was studied as a function of fibronectin concentration and bead diameter. Cells were incubated with radioactive pFN-coated beads, and total bead binding (cell surface or ingested) was measured as total radioactivity associated with the cells. Of the bound beads, those that also were phagocyto...

in this study chitosan hydrogel beads with porosity ~ 0.86 and diameter ~ 20.07 mm were prepared from 85 % deacetylated chitosan for removal of cd2+ ions from aqueous solutions.  chitosan powder was dissolved into dilute acetic acid as solvent and formed into spherical beads using a phase inversion technique. the effect of temperature, initial concentration of cd2+ ions, and the period of agita...