Genetic mutations disrupting the function of signaling lymphocytic activation molecule-associated protein (SAP) lead to T cell intrinsic defects in T cell-dependent Ab responses. To better understand how SAP enables Th cells to help B cells, we first assessed whether molecules important for B cell help are dysregulated in SAP-deficient (SAP knockout (KO)) mice. CD40 ligand (CD40L) expression wa...

BACKGROUND AND OBJECTIVES Although new technology of assistive listening device leads many hard of hearing children to be mainstreamed in public school programs, many clinicians and teachers still wonder whether the children are able to understand all instruction, access educational materials, and have social skills in the school. The purpose of this study is to develop a school adaptation prog...

Most observers would agree that the Sarbanes-Oxley Act (SOA) is the single most important piece of legislation affecting corporate governance, financial disclosure and the practice of public accounting. On the other hand, the SAP system is the most widely used ERP (Enterprise Resource Planning) system in the world. There are thousands of seamlessly linked components and subsystems. Conducting s...

SLAM (signaling lymphocyte activation molecule)-associated protein (SAP) is a Src homology 2 (SH2) domain-containing adaptor expressed in T cells and natural killer cells. Its essential role in immune responses is underscored by the recent finding that mutations in SAP result in a rare but fatal X-linked lymphoproliferative disease (XLP). Although SAP is known to associate with SLAM-family rece...

This work provides a design for two types of sensors, based on the thermal dissipation and heat ratio methods of sap flow calculation, for moderate to large scale deployments for the purpose of monitoring tree transpiration. These designs include a procedure for making these sensors, a quality control method for the final products, and a complete list of components with vendors and pricing info...

SaP::GPU is a solver developed in the Simulation Based Engineering Lab (SBEL) [1] to solve large banded and sparse linear systems on the GPU. This report contributes the performance comparison of the banded solver of SaP::GPU and Intel’s Math Kernel Library [2] on a large set of synthetic problems. The results of several numerical experiments indicate that when it is used in conjunction with la...

SLAM family receptors regulate activation and inhibition in immunity through recruitment of activating and inhibitory SH2 domain containing proteins to immunoreceptor tyrosine based switch motifs (ITSMs). Binding of the adaptors, SAP and EAT-2 to ITSMs in the cytoplasmic regions of SLAM family receptors is important for activation. We analysed the fine specificity of SLAM family receptor phosph...

PURPOSE We evaluated threshold saccadic vector optokinetic perimetry (SVOP) and compared results to standard automated perimetry (SAP). METHODS A cross-sectional study was done including 162 subjects (103 with glaucoma and 59 healthy subjects) recruited at a university hospital. All subjects underwent SAP and threshold SVOP. SVOP uses an eye tracker to monitor eye movement responses to stimul...

Sorghum is among the most important forages used in arid and semi-arid regions of south-eastern Iran. Application of some materials such as super absorbent polymer (SAP) in soil can increase soil water storage capacity and increase water use efficiency. The aim of the study was to estimate the relative membrane permeability of sorghum under irrigation regimes and superabsorbent polymer applicat...

In order to optimize the economical use of SAP software systems and to increase the cost effectiveness of the SAP investment, the available SAP standard system should be implemented in the best possible way. While standard functionality has no negative effects on maintenance and operating cost, modification of the standard has the potential to drive costs (Markus et al. 2000). An integrated met...