This study was carried out to determine the toxicity and biochemical morphophysiological changes caused by Serjania erecta leaf aqueous extract in pacu (Piaractus mesopotamicus). For acute testing (CL50-4h), juveniles were exposed during 4 h concentrations of 2.5, 12.5, 25, 50, 100, 150 µg mL-1, which added directly water tanks. In control group, animals kept free from extract. CL50-4 estimated...