Depression is one of the most common and persistent nonmotor syndromes occurring in 35% of patients diagnosed with PD. However, little information is known about the longitudinal study of its natural history of depression in PD. In this study, we identified 110 patients who are diagnosed with idiopathic PD and recruited them for assessing information about their PD related motor and nonmotor sy...

BACKGROUND The Hamilton Depression Rating Scale retains its primacy in research. There have been recent important critiques. It is clear that instructions provided by its author are widely overlooked. METHOD A survey of the present use of the HDRS was conducted by inspection of five major journals publishing studies in the field of psychiatry. Note was especially made of whether a recognised ...

In the first of these, Barakat and Redzic [this issue, pp. 3–14] highlight how basic science research into the underlying mechanisms of cerebral ischemia may lead to novel therapies for this potentially fatal condition. Cardiac arrest and strokes can lead to ischemia in the brain, either focal (limited to a small region of the brain) or global (widespread and covering large parts of the brain)....

Using demographic multi-state, cohort-component methods, we produce projections for 120 countries (covering 93% of the world population in 2005) by five-year age groups, sex, and four levels of educational attainment for the years 2005-2050. Taking into account differentials in fertility and mortality by education level, we present the first systematic global educational attainment projections ...

In this issue, our articles explore the often-fragile interaction of scholars, local activists, and practitioners who are blending ideas philosophies at home abroad to find a more just equitable food system that can help save planet. Or, put their collaborative efforts viscerally, ways for human beings themselves from themselves. An example weaving Western Indigenous knowledge is on cover issue...

Human schistosomiasis is one of the most common Neglected Tropical Diseases (NTDs); it is an intravascular parasite caused by the trematode blood fluke (Schistosoma). Most human infections are caused by S. haematobium, S. mansoni, and S. japonicum. An estimated total of 237 people are infected worldwide, and 732 million people are at risk of being infected. In the Middle East and North Africa (...

AIM The objective of this study was to analyze the changes in depressive and extrapyramidal symptomatology during glycine augmentation of antipsychotic treatment in patients with schizophrenia. MATERIALS AND METHODS Twenty-nine schizophrenic patients (ICD-10) with predominant negative symptoms in stable mental state participated in a 10-week open-label prospective study. Patients received sta...

A pharmacokinetic study was done on 10 depressed patients (DSM-III-R 296.3). The patients were treated with Sintamil (R) (nitroxazepine HCl) with titrated dose from 75 mg to 225 mg for 6 weeks. Plasma levels of nitroxazepine (Sintamil (R)) and its metabolites desmethyl (D), N-oxide (N-O) and carboxylic acid (c) were estimated. Anti-depressant efficacy was judged by reduction in Hamilton Rating ...

RefeRences Conte, F., Carobbi, G. Errico, B. M., and Ficca, G. (2012). The effects of pre-sleep learning on sleep continuity, stability, and organization in elderly individuals. Front. Neurol. 3:109. doi: 10.3389/fneur.2012.00109 Fogel, S., Martin, N., Lafortune, M., Barakat, M. Debas, K., Laventure, S., et al. (2012). NREM sleep oscillations and brain plasticity in aging. Front. Neurol. 3:176....

jahez is one m of the most prominent character in the field of science and literature in the world.in addition to his proficiency in sciences,education and literature,he is one of the most celebrated one in discourse science and beliefs.he innovated a new religion called “jahezie religion’’ in the history of discourse  cience.from among his important works which are famous in all over the world...