نتایج جستجو برای: bacterial toxins
تعداد نتایج: 221164 فیلتر نتایج به سال:
A significant number of bacteria, including the emerging multidrug-resistant “superbugs,” such as Pseudomonas aeruginosa, Clostridium difficile, Staphylococcus aureus, and Escherichia coli, secrete highly potent exotoxins with no antitoxins currently available to disable them. Several bacterial toxins, such as the botulinum neurotoxin (BoNT) of Clostridium botulinum, can be aerosolized and used...
Human defensins are innate immune defense peptides with a remarkably broad repertoire of anti-pathogen activities. In addition to modulating immune response, inflammation, and angiogenesis, disintegrating bacterial membranes, and inactivating bacterial toxins, defensins are known to intercept various viruses at different stages of their life cycles, while remaining relatively benign towards hum...
To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings, X-ray crystallography, protein engineering, and computational methods have generated a large body of knowledge about the basic principles of cha...
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