Human babesiosis (caused by Babesia microti) and Lyme disease (caused by Borrelia burgdorferi) are among the most common tick-transmitted zoonoses. Recent evidence indicates that both diseases are emerging in the northeastern and Great Lakes regions of the United States as the deer tick (Ixodes scapularis), which transmits both infections, increases in geographic distribution. Because B. microt...

Bovine babesiosis also known as redwater, is the worldwide most important hemoparasitic diseases of cattle that causes significant morbidity and mortality. It is caused by intra-erythrocytic protozoan parasites of the genus Babesia, which affects a wide range of domestic and wild animals and occasionally humans. Two important Babesia species: B. bigemina and B bovis infect cattle. They are wide...

The apicomplexan Babesia microti is the primary causative agent of human babesiosis, one of the most broadly distributed tick-borne diseases worldwide. B. microti undergoes a complex lifecycle within both the mammalian host and the tick vector, and employs several different specific molecular mechanisms to enter host cells. Enolase, the key glycolytic enzyme in intracellular glucose metabolism,...

Babesiosis is a malaria-like illness caused by the intraerythrocytic parasite Babesia microti and is transmitted by the same tick that transmits Borrelia burgdorferi, the causative agent of Lyme disease. Babesiosis is well recognized in adult residents of southern New England and New York but has been described in only five children. To determine whether children are infected with B microti les...

The ticks Rhipicephalus (Boophilus) annulatus and R. (B.) microplus, commonly known as cattle and southern cattle tick, respectively, impede the development and sustainability of livestock industries throughout tropical and other world regions. They affect animal productivity and wellbeing directly through their obligate blood-feeding habit and indirectly by serving as vectors of the infectious...

Previously reported babesiosis cases in children have been mostly acquired by blood transfusion (10). The patient had no history of transfusions with blood products and had never traveled outside his home town before disease onset. Although he and his parents did not recall any tick bites, he was at high risk for exposure to ticks because he often played with his dog, which frequently went outd...

Babesiosis is a potentially life-threatening zoonotic disease that is endemic to the northeastern United States and increasing in prevalence worldwide. Transmitted by the same Ixodes tick responsible for Lyme disease, the intraerythrocytic parasite Babesia causes a wide range of clinical presentations--from asymptomatic carriage to a fulminant course with rapid deterioration. Symptoms typically...

The effect of tick control on the infection rates of Babesia bovis and Babesia bigemina are reported for 6 geographical regions in South Africa. Under conditions of poor tick control the situation for B. bovis was one of apparent enzootic instability in the 2 regions where its presence was recorded. Under similar conditions the situation for B. bigemina was generally stable. With good tick cont...

BACKGROUND Babesiosis is a zoonotic disease transmitted by the Ixodes tick species. Infection often results in sub-clinical manifestations; however, patients with this disease can become critically ill. Splenic rupture has been a previously reported complication of babesiosis, but treatment has always led to splenectomy. Asplenia places a patient at greater risk for overwhelming post-splenectom...