نتایج جستجو برای: b thalassemia

تعداد نتایج: 917848  

2014
Manit Nuinoon Kwanta Kruachan Warachaya Sengking Dararat Horpet Ubol Sungyuan

Thalassemia and hemoglobin E (Hb E) are common in Thailand. Individuals with thalassemia trait usually have a normal hemoglobin concentration or mild anemia. Therefore, thalassemic individuals who have minimum acceptable Hb level may be accepted as blood donors. This study was aimed at determining the frequency of α-thalassemia 1 trait, β-thalassemia trait, and Hb E-related syndromes in Souther...

2007
Inusha Panigrahi R. K. Marwaha

a s ite ho ste d b y M ed kn ow P ub lic ati on s ( ww w Thalassemias are common genetic disorders in the Indian subcontinent.[1] Thalassemia major is the severe phenotype which requires lifelong transfusions and bone marrow transplantation is the only curative option available. Knowledge of the ethnic and geographic origin would enable molecular analysis to be tailored, keeping in view the spe...

2014
Dudley J. Pennell John B. Porter Antonio Piga Yongrong Lai Amal El-Beshlawy Khawla M. Belhoul Mohsen Elalfy Akif Yesilipek Yurdanur Kilinç Tomasz Lawniczek Dany Habr Marianne Weisskopf Yiyun Zhang Yesim Aydinok

A 1-year randomized controlled trial of deferasirox vs deferoxamine for myocardial iron removal in b-thalassemia major (CORDELIA) Dudley J. Pennell, John B. Porter, Antonio Piga, Yongrong Lai, Amal El-Beshlawy, Khawla M. Belhoul, Mohsen Elalfy, Akif Yesilipek, Yurdanur Kilinç, Tomasz Lawniczek, Dany Habr, Marianne Weisskopf, Yiyun Zhang, and Yesim Aydinok, on behalf of the CORDELIA study invest...

Journal: :Riset Informasi Kesehatan 2022

Background: Pain during invasive procedures is an unpleasant thing experienced by all children when hospitalized, including with acute illnesses or chronic diseases such as thalassemia. Nurses need to implement interventions from atraumatic care reduce the pain felt children, providing audiovisual distraction techniques. This study aimed see difference in thalassemia and non-thalassemia after b...

Background: Although regular frequent blood transfusion improves overall survival of multi-transfused patients like β-thalassemic ones, it carries a definite risk of infection with blood-borne viruses such as viral hepatitis. This study was done to determine seropositivity of hepatitis B virus (HBV), hepatitis C virus (HCV), and Human Immunedeficiency Virus (HIV) infections among β-th...

Journal: :Thalassemia Reports 2022

This is a report of couple with abnormal hematological indices who were investigated for α & β-thalassemia mutations. Based on CBC and capillary hemoglobin electrophoresis results, the male female subjects β α-thalassemia carriers, respectively. Multiplex-Gap-PCR Sanger sequencing techniques used identification mutations β-globin genes. The DNA test showed presence c.315 + 1 G > A mutati...

Background: b-thalassemia major is a common hereditary blood disease that can affect patients’ oral health and quality of life. The present study aims to determine the relationship between health of deciduous teeth and the Oral Health-Related Quality of Life (OHRQoL) in children diagnosed with β-thalassemia major compared with healthy children. Materials and Methods This cross-sectional study w...

Journal: :Journal of lipid research 2010
Alexandros D Tselepis George Hahalis Constantinos C Tellis Eleni C Papavasiliou Panagiota T Mylona Alexandra Kourakli Dimitrios C Alexopoulos

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an independent cardiovascular risk factor. We investigated the plasma levels of Lp-PLA(2) activity and mass as a function of plasma lipid levels, LDL subclass profile, and oxidative stress in patients with β-thalassemia. Thirty-five patients with β-thalassemia major (β-TM) and 25 patients with β-thalassemia intermedia (β-TI) participated ...

Journal: :International journal of innovative research in medical science 2023

Background: Thalassemia is an inherited disease. major patients are transfusion-dependent and very much prone to transfusion-transmitted viral infections. So, this study was conducted determine the prevalence various determinants, contributing in blood transfusion transmitted infection among them. Methodology: A 12-month longitudinal research on thalassemia who met inclusion criteria were regis...

Journal: :The Southeast Asian journal of tropical medicine and public health 1992
S Fucharoen P Winichagoon

In Southeast Asia alpha-thalassemia, beta-thalassemia, hemoglobin (Hb) E and Hb Constant Spring are prevalent. The gene frequencies of alpha-thalassemia reach 30-40% in Northern Thailand and Laos. beta-Thalassemia gene frequencies vary between 1 and 9%. Hb E is the hallmark of Southeast Asia attaining a frequency of 50-60% at the junction of Thailand, Laos, and Cambodia. Hb Constant Spring gene...

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