Correspondence: MPS, e-mail . Received 30 March 2009 and revised version accepted 16 July 2009. Competing interests: none declared. Margosa oil induced toxic encephalopathy is a recognised entity [1]. It presents with vomiting which begins minutes to hours after ingestion, followed by drowsiness and generalised seizures. Hepatomegaly, elevated liver enzymes, metabo...

The antifeedant and anthelmintic activities of crude extracts of the shells of Anacardium occidentale were studied by comparing it's activity with the activity of Azadirachta indica A Juss (Kernel), a commercial standard. The test extracts of A. occidentale in petroleum ether, dichloromethane: methanol showed better activities compared to A. Indica. To Study the anthelmintic activity, the addit...

The efficiency of different natural plant extracts and of the chemical fungicide Micronite was carried out to determine their effects on the soil fungi particularly phytopathogenic and mycotoxigenic fungi Fusarium oxysporum, Alternaria alternata and Aspergillus flavus. In vitro studies were carried out to test the antifungal activity of 4 plant extracts; performed with either cold distilled wat...

The aim of the study was to investigate the thrombolytic activity of Punica granatum and Azadirachta indica over canine, bovine, caprine and avian blood clot using streptokinase and water as positive and negative control respectively. Using an in vitro thrombolytic model, the clot lysis activity of A. indica was observed as 48.06±0.59%, 50.01±1%, 47.6±0.69% and 28.03±0.35% and of P. granatum as...

The present study was carried out to investigate the anti-inflammatory, antipyretic and analgesic effect of the crude ethanol extract of Azadirachta indica leaves on experimental rat model at three different dose levels100, 200 and 300 mg/kg, respectively. Hot plate test were used to assess analgesic activity, formalin induced inflammation was used for anti-inflammatory study and baker’s yeast ...

objective: the present study was an attempt to study total phenolic content and antioxidant property of the crude ethanolic extract of the roots of azadirachta indica (a. indica). materials and methods: to evaluate the antioxidant properties of the crude extract, some complementary test systems, namely dpph free radical scavenging assay, reducing power assay, and ferrous ion chelating ability a...

The effect of different pretreatment methods, temperature, and enzyme concentration on ethanol production from 8 lignocellulosic agrowaste by simultaneous saccharification and fermentation (SSF) using recombinant cellulase and Saccharomyces cerevisiae were studied. Recombinant cellulase was isolated from E. coli BL21 cells transformed with CtLic26A-Cel5-CBM11 full-length gene from Clostridium t...

Azadirachta indica (neem) is the only source of azadirachtin, which is known for its insecticide activity. Melia azedarach is a related species of A. indica, widely distributed in the south of China. In this study, the leaf transcriptomes of these two Meliaceae plants were sequenced. More than 40 million clean reads were generated from each library. About 80 % of A. indica reads were mapped to ...

BACKGROUND Azadirachta indica has been reported to correct altered glycaemia in diabetes. OBJECTIVE The aqueous extract of A. indica leaf and bark has been evaluated for its effect on antioxidant status of alloxan diabetic rats and compared with insulin treatment. MATERIALS AND METHODS The oral effective dose of A. indica leaf (500 mg/kg body weight) and A. indica bark (100 mg/kg body weigh...

Screening of phenolic constituents in leaves of Cedrela serrata, Toona ciliata, Azadirachta indica and Melia azedarach was done by reversed phase high performance liquid chromatography (RP-HPLC). The phenolic compounds were identified by comparison with authentic standards. The phenolic acids identified in all plants leaves extract were gallic acid, protocatechuic acid, p-hydroxy benzoic acid, ...