Objective. To investigate the efficacy of 6 weeks of daily low-dose oral prednisolone in improving pain, mobility, and systemic low-grade inflammation in the short term and whether the effect would be sustained at 12 weeks in older adults with moderate to severe knee osteoarthritis (OA). Methods.A total of 125 patients with primary knee OA were randomized 1:1; 63 received 7.5 mg/day of predniso...
