The etiopathogenesis of many autoimmune disorders has not been identified. The aim of this paper is to focus on the involvement of bacterial exposure, as an environmental factor, in the pathogenesis of autoimmune pancreatitis (AIP), which is broadly categorized as autoimmune disorders involving pancreatic lesions. Avirulent and/or commensal bacteria, which may have an important role(s) as initi...

BACKGROUND Autoimmune encephalitis might coexist in patients with autoimmune demyelinating disorders. CASE REPORT We report on a case of a 45-year-old female multiple sclerosis (MS) patient presenting with acute onset short-term memory loss, altered mental status, inflammatory cerebrospinal fluid (CSF) findings and an MRI lesion on the left temporal lobe. An extensive panel for neuronal autoant...

myelodysplastic syndromes (mds) are a group of hematological disorders ranging from chronic refractory anemia to leukemia. there are some reports about association of mds with autoimmune disorders and vasculitis. in this study we describe a patient with mds and vasculitis presenting with central nervous system (cns) involvement. a clinical response to immunosuppressive therapy was also observed...

Autoimmune pancreatitis (AIP) is a rare disorder of presumed autoimmune etiology with specific pathologic features, and is an increasingly recognized clinical condition. AIP is characterized histologically by fibrosis with dense infiltration of T lymphocytes and IgG4positive plasma cells in the peripancreatic and interlobular area of the pancreas (1-4). Patients with AIP usually have serum mark...

autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. hepatitis c virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis c virus infection and some autoimmune disease has been st...

Pregnant women with autoimmune rheumatic diseases, especially systemic lupus erythematosus (SLE) and systemic sclerosis, are at high risk of maternal disease flares, adverse fetal outcomes and potential drug teratogenic effects, making the management of these women particularly challenging. With improvements in diagnosis and treatment, however, these risks can be minimized by appropriate timing...

OPINION STATEMENT Autoimmune neuromuscular disorders in childhood include Guillain-Barré syndrome and its variants, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), juvenile myasthenia gravis (JMG), and juvenile dermatomyositis (JDM), along with other disorders rarely seen in childhood. In general, these diseases have not been studied as extensively as they have been in adults....