نتایج جستجو برای: autoantigens

تعداد نتایج: 4179  

Journal: :Journal of Experimental Medicine 1971

Journal: :Journal of Investigative Dermatology 1993

2015
Douglas C. Chang Paolo Piaggi Robert L. Hanson William C. Knowler John Bucci Guene Thio Maximilian G. Hohenadel Clifton Bogardus Jonathan Krakoff Salvatore V Pizzo

New biomarkers for type 2 diabetes mellitus (T2DM) may aid diagnosis, drug development or clinical treatment. Evidence is increasing for the adaptive immune system's role in T2DM and suggests the presence of unidentified autoantibodies. While high-density protein microarrays have emerged as a useful technology to identify possible novel autoantigens in autoimmune diseases, its application in T2...

2016
Xiaobo Meng Peyman Ezzati Irene Smolik Charles N. Bernstein Carol Ann Hitchon Hani S. El-Gabalawy

Anti-citrullinated protein antibodies (ACPA) have become an integral part of the clinical definition of rheumatoid arthritis, and are hypothesized to be important in the immunopathogenesis of this autoimmune disease. Several citrullinated proteins have been demonstrated to serve as candidate autoantigens for the ACPA, based on in vitro immune reactions between citrullinated peptides/proteins an...

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