AUTO–positive end-expiratory pressure (auto-PEEP) is well described in patients with expiratory airflow obstruction, including those who require one-lung ventilation. Unfortunately, detecting auto-PEEP with most anesthesia ventilators is difficult. We report an unusual presentation of auto-PEEP during one-lung ventilation in which a reliable method of confirming lung separation quickly directed...

Yeast KEX2 protease was examined as a potential model for a human proprotein convertase and, in all respects, mimicked the predicted properties of a proalbumin convertase. The enzyme rapidly cleaved the propeptide Arg-Gly-Val-Phe-Arg-Arg from the NH2-terminal end of proalbumin but, unlike trypsin, failed to cleave physiologically unprocessed human proalbumin variants. There was little or no cle...

Computational prediction of origin of replication (ORI) has been of great interest in bioinformatics and several methods including GC Skew, Z curve, auto-correlation etc. have been explored in the past. In this paper, we have extended the auto-correlation method to predict ORI location with much higher resolution for prokaryotes. The proposed complex correlation method (iCorr) converts the geno...

Stacked denoising auto encoders (DAEs) are well known to learn useful deep representations, which can be used to improve supervised training by initializing a deep network. We investigate a training scheme of a deep DAE, where DAE layers are gradually added and keep adapting as additional layers are added. We show that in the regime of mid-sized datasets, this gradual training provides a small ...

Chronic venous diseases (CVD), including varicose veins, are among the most common in developed countries Europe and United States affect one third to half of population, especially women. Among many achievements knowledge pathogenesis achievements, it should be noted identification role matrix metalloproteinases (MMPs) as important mediators degenerative process associated with onset progressi...