نتایج جستجو برای: auto antigen

تعداد نتایج: 226878  

Journal: :CoRR 2014
Thomas Karcher Christopher Guckes Walter F. Tichy

Thomas Karcher Institute for Program Structures and Data Organization Karlsruhe Institute of Technology 76128 Karlsruhe, Germany [email protected] Christopher Guckes Institute for Program Structures and Data Organization Karlsruhe Institute of Technology 76128 Karlsruhe, Germany [email protected] Walter F. Tichy Institute for Program Structures and Data Organization Karlsruhe Institute...

Journal: :Computer Communications 2008
Valentina Casola Emilio Pasquale Mancini Nicola Mazzocca Massimiliano Rak Umberto Villano

Service-oriented architectures (SOA) and, in particular, Web Services designs are widely adopted for the development of interoperable systems. In a dynamic scenario, a composed service may exploit component services in order to complete its task; composed services are variously distributed, and offered by different providers in different security domains and under different load conditions. So,...

Journal: :The European respiratory journal 2007
B N Lambrecht L M van den Toorn

A role for inflammatory processes in the pathogenesis of pulmonary arterial hypertension (PAH) has been proposed, since inflammatory infiltrates surrounding remodelled vessels in human and experimental PAH have been described by several groups [1, 2]. Increased levels and expression of cytokines, chemokines and lipid mediators have been found in the blood, lung parenchyma and affected pulmonary...

2015
Massimo Maddaloni Irina Kochetkova SangMu Jun Gayle Callis Theresa Thornburg David W. Pascual

Autoimmune diseases arise from the loss of tolerance to self, and because the etiologies of such diseases are largely unknown, symptomatic treatments rely on anti-inflammatory and analgesic agents. Tolerogenic treatments that can reverse disease are preferred, but again, often thwarted by not knowing the responsible auto-antigens (auto-Ags). Hence, a viable alternative to stimulating regulatory...

Journal: :Blood 2009
Marcello Rotta Barry E Storer Firoozeh Sahebi Judith A Shizuru Benedetto Bruno Thoralf Lange Edward D Agura Peter A McSweeney Michael A Pulsipher Parameswaran Hari Richard T Maziarz Thomas R Chauncey Frederick R Appelbaum Mohamed L Sorror William Bensinger Brenda M Sandmaier Rainer F Storb David G Maloney

Autologous hematopoietic cell transplantation (HCT) followed by nonmyeloablative allogeneic HCT (auto/alloHCT) provides cytoreduction and graft-versus-myeloma effects. We report on long-term outcomes of 102 patients with multiple myeloma who received auto/alloHCT with a median follow-up of 6.3 years. Treatment consisted of high-dose melphalan and autograft followed by 2-Gy total body irradiatio...

Journal: :Rheumatology 2008
S Suzuki T Satoh S Sato M Otomo Y Hirayama H Sato M Kawai T Ishihara N Suzuki M Kuwana

OBJECTIVE Auto-antibodies to signal recognition particle (SRP) are known to be specific to PM among rheumatic disorders, but the specificity in myopathic diseases remains unclear. The clinical utility of anti-SRP antibody in the differential diagnosis of myopathies has not been studied. The aim of the present study was to elucidate whether detection of anti-SRP antibody can discriminate of PM f...

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