The selectivity of our previously described gold-catalyzed tandem reaction, 1,2-indole migration followed by aura-iso-Nazarov cyclization, of 3-propargylindoles bearing (hetero)aromatic substituents at both the propargylic and terminal positions, was reversed by the proper choice of the catalyst and the reaction conditions. Thus, 3-(inden-2-yl)indoles, derived from an aura-Nazarov cyclization (...

there are several conflicting reports about the eeg of the migraineurs. in this study we report the ictal and interictal eegs of 100 migraineurs, in comparison with control group. the range age for patient and control groups were 9-48 (mean: 26 ± 1.8) and 10-46 (mean: 23 ± 2.1) years respectively. 32% of the patients were less than 14 years old and the remaining 68% were more than 14 years. in ...

Condition monitoring systems for prognostics and diagnostics can enable large and complex systems to be operated more safely, at a lower cost and have a longer lifetime than is possible without them. AURA Alert is a condition monitoring system that uses a fast approximate k Nearest Neighbour (kNN) search of a timeseries database containing known system states to identify anomalous system behavi...

Post-transcriptional regulation of gene expression (PTR) has been object of a rising interest in the latest years, gaining wide recognition as the most important determinant of protein levels and cell phenotypes. In consequence to this interest, huge amounts of data have been and are being collected every day primarily thanks to the advent of the new high-throughput techniques such as polysomal...

Purpose Building on Walter Benjamin's philosophical reflections aura and authenticity, this article aims to conceptualise theorise brand aura. Design/methodology/approach This extends understanding of within the management, marketing tourism literature with reference framing authenticity in time space. Findings Within a Benjaminian framework theorises offers conceptualisation antecedents It exp...

In this issue of Cephalalgia, Dr Jakob Moller Hansen and his colleagues report a series of very interesting experiments in which they successfully induced migraine-like attacks in patients with migraine with aura via infusion of calcitonin gene related peptide (CGRP). This work echoes similar experiments carried out by the Copenhagen group using the nitric oxide donor, glycerol trinitrate (GTN)...

CONTEXT Migraine with aura has been associated with an adverse cardiovascular risk profile and prothrombotic factors that, along with migraine-specific physiology, may increase the risk of vascular events. Although migraine with aura has been associated with increased risk of ischemic stroke, an association with cardiovascular disease (CVD) and, specifically, coronary events remains unclear. ...

OBJECTIVES To assess the clinical performance of the Ambu Aura-i (Aura-i) in children. AIM To compare the Aura-i with the air-Q intubating laryngeal airway (air-Q) for the purposes of fiberoptic-guided tracheal intubation. BACKGROUND The Aura-i is a new supraglottic airway designed for tracheal intubation. MATERIALS/METHODS One hundred twenty children, ages 1 month to 6 years, were random...

A relationship between migraine with aura and the presence of right-to-left shunts has been reported in two studies. Right-to-left shunts are also associated with some forms of decompression illness. While conducting research in divers with decompression illness, it was our impression that divers with a large shunt often had a history of migraine with aura in everyday life and after dives. Ther...