UNLABELLED BACKGROUND Thyroid hemiagenesis is a rare anomaly, more commonly seen on the left side (ratio 4:1) and in females (ratio 3:1). The first to describe this anomaly was Handfield Jones in 1852. CASE PRESENTATION We present a 66 year old female patient with right thyroid hemiagenesis, parathyroid adenoma on the side of hemiagenesis and parathyroid hyperplasia on the contralateral si...

INTRODUCTION Parathyroid crisis due to ectopic parathyroid adenomas can pose diagnostic and management challenges, since it is quite rare in clinical practice. CLINICAL FINDINGS/PATIENT CONCERNS A 67-year-old Chinese male presented as a parathyroid crisis due to an ectopic mediastinal parathyroid adenoma with his serum calcium and PTH markedly increased in short time. An ultrasonography and c...

OBJECTIVE To describe a patient presenting with the rare constellation of synchronous parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma. METHODS We summarize the clinical presentation, diagnostic work-up, surgical management, and pathologic features of our patient and review the pertinent literature. RESULTS The patient was a 59-year-old man who presented with seve...

INTRODUCTION Hypercalcemia can be associated with vitamin D (1,25(OH)2D3) -mediated granulomatous disorders in addition to primary hyperparathyroidism (PHPT). Although most patients with granulomatous disease-related hypercalcemia are asymptomatic, symptoms and signs of chronic hypercalcemia can occur. There are many reports about co-presentation of a parathyroid adenoma and a granulomatous dis...

Hypercalcemia is a rare but serious metabolic condition that may lead to end-organ damage. Primary hyperparathyroidism disease in children and adolescents parathyroid adenoma the most common cause. Most of patients are clinically symptomatic present signs or symptoms hypercalcemia. The aim this report describe two case hypercalcemia due presenting with different clinical findings. 14 years old ...

OBJECTIVE Angiogenic growth factors bFGF and VEGF ensure vascularisation of the growing tumor tissue. We decided to investigate their peripheral serum concentrations in patients with thyroid gland adenoma and papillary carcinoma and with parathyroid adenoma. We wanted to find the possible serum marker of these tumor diseases. METHODS 28 patients with thyroid gland tumor (14x adenoma, 14x papi...

HYPOTHESIS We hypothesize that false-negative results using the rapid intraoperative parathyroid hormone (IOPTH) assay can be caused by spikes in the level of parathyroid hormone that occur during mobilization of the adenoma. DESIGN Retrospective analysis of a case series. SETTING University tertiary care center. PATIENTS Ten consecutive patients with primary hyperparathyroidism. INTERV...

It is very difficult to differentiate follicular adenoma from follicular carcinoma in thyroid follicular lesions. The authors investigated the biological behavior of these thyroid follicular lesions using immunohistochemical techniques. Specimens taken from normal thyroid, 2 cases; follicular adenoma, 9; atypical adenoma, 7; and follicular carcinoma, 8; were observed. Proliferating cell nuclear...