نتایج جستجو برای: atp binding cassette transporter a1

تعداد نتایج: 528933  

Journal: :Life Sciences 2021

Low testosterone in men is associated with increased cardiovascular events and mortality. Testosterone has beneficial effects on several risk factors including cholesterol, endothelial dysfunction inflammation as key mediators of atherosclerosis. Although evidence suggests anti-atherogenic, its mechanism action unknown. The present study investigates whether exerts anti-atherogenic by stimulati...

Journal: :Plant physiology 2005
Mihoko Otani Nobukazu Shitan Kyoko Sakai Enrico Martinoia Fumihiko Sato Kazufumi Yazaki

Alkaloids comprise one of the largest groups of plant secondary metabolites. Many of them exhibit strong biological activities, and, in most cases, they are accumulated in the central vacuole of alkaloid-producing plants after synthesis. However, the mechanisms involved in alkaloid transport across the tonoplast are only poorly understood. In this study, we analyzed the vacuolar transport mecha...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2014
Irena D Ignatova Ira G Schulman

A critical event in the development of atherosclerosis is the recruitment of macrophages to the underlying epithelial layer of blood vessel walls and the uncontrolled uptake of oxi-dized/modified cholesterol. Continued accumulation of oxi-dized/modified cholesterol by macrophages and an associated inflammatory response leads to foam cell formation and the initiation of atherosclerosis. 1 Revers...

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