Hypercholesterolemia is involved in the development of atherosclerosis and a risk factor for coronary artery disease, stroke, peripheral vascular disease. This paper deals with mechanism hypercholesterolemic atherosclerosis. increases formation numerous atherogenic biomolecules including reactive oxygen species (ROS), proinflammatory cytokines [interleukin (IL)-1, IL-2, IL-6, IL-8, tumor necros...

atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. disturbed adiponectin actions through its receptor, (adipor1 and adipor2) may be involved in atheros...

introduction: sudden sensorineural hearing-loss (ssnhl) patients constitute approximately 2–3% of referrals to ear, nose and throat (ent) clinics. several predisposing factors have been proposed for this condition; one of which is vascular disorders and perfusion compromise. in this research the atherosclerotic changes and their known risk factors are studied in ssnhl patients.   materials and ...

Inflammation is a key component of atherosclerosis. Abundant preclinical data support the hypothesis that atherosclerosis is a chronic inflammatory disorder.1,2 Indeed, clinical trial data now provide evidence that inflammation, as reflected in serum markers such as C-reactive protein and interleukin-6, is a strong risk factor for the development and progression of atherosclerosis.3,4 The role ...