The present study was planned to test the efficacy of Moringa oleifera on undesirable skin sebum secreted by sebaceous glands during winter season in humans. For this purpose, an extract of Moringa leaves was prepared due to strong antioxidant activity. 3% Moringa leaves extract was incorporated in active cream and the base was without extract. The study was conducted during the winter season (...

A protein called P36 holds the key to how different species of malaria parasite invade liver cells.

The emergence of networked information and communication has transformed the accessibility and delivery of scholarly information and fundamentally impacted on the processes of research and scholarly communication. The purpose of this study is to investigate disciplinary differences in the use of networked information for research and scholarly communication at Sultan Qaboos University, Oman. Th...

Acute lung injury (ALI) is a complex and devastating illness, often occurring in the setting of sepsis and trauma. Despite recent advances in the understanding and treatment of ALI, pathogenic mechanisms and genetic modifiers in ALI remain incompletely understood. Furthermore, there has been increasing interest in the identification of genetic variations that contribute to ALI susceptibility an...

Among a number of clinical factors, bacterial infection is one of the most common causes of acute lung injury (ALI), a serious complication that carries a high risk of mortality (~40%). During the process of ALI, intense local and systemic inflammation is elicited, which exacerbates the injury. Neutrophil infiltration into airspace is observed in early stage of ALI, and is required for the full...

Malaria-associated acute lung injury/acute respiratory distress syndrome (ALI/ARDS) often results in morbidity and mortality. Murine models to study malaria-associated ALI/ARDS have been described; we still lack a method of distinguishing which mice will develop ALI/ARDS before death. This work aimed to characterize malaria-associated ALI/ARDS in a murine model and to demonstrate the first meth...

Tissue factor (TF) is a critical mediator of direct acute lung injury (ALI) with global TF deficiency resulting in increased airspace inflammation, alveolar-capillary permeability, and alveolar hemorrhage after intra-tracheal lipopolysaccharide (LPS). In the lung, TF is expressed diffusely on the lung epithelium and intensely on cells of the myeloid lineage. We recently reported that TF on the ...

BACKGROUND Acute lung injury (ALI) is an example of a critical care syndrome with limited treatment options once the condition is fully established. Despite improved understanding of pathophysiology of ALI, the clinical impact has been limited to improvements in supportive treatment. On the other hand, little has been done on the prevention of ALI. Olmsted County, MN, geographically isolated fr...