Asymmetric 1,3-dipolar cycloadditions between 1,2-diaza-1,3-dienes and chiral non-racemic nitrones to give 3-substituted-5-diazenyl isoxazolidines were studied both experimentally and theoretically. Whereas cyclic nitrones provide complete selectivity for the cycloaddition reaction (only one isomer is obtained), acyclic nitrones derived from D-glyceraldehyde and D-galactose lead to 1 : 1 mixtur...

Catalytic asymmetric 1,3-dipolar cycloadditions of azomethine ylides have turned out to be one of the most efficient methods for the preparation of enantioenriched pyrrolidines. The past decade has witnessed the development of a bunch of well-defined catalytic systems capable of affording excellent diastereo and enantioselectivities. Recently, a great effort has been focused on expanding the sc...

Pyrinodemin A 1, a cytotoxic marine alkaloid, was synthesized in a convergent and enantioselective fashion. The key steps are an asymmetric intramolecular dipolar cycloaddition of an oxazoline N-oxide to introduce the bicyclic ring system of the molecule, a cuprate coupling for the extension of the saturated chain and a B-alkyl Suzuki coupling for the introduction of a 3-pyridyl moiety. Reducti...

In general, the optical binding force between identical particles is thought to be symmetric. However, we demonstrate analytically a counterintuitively asymmetric longitudinal two electric and magnetic dipolar dielectric particles. This homodimer confined in counterpropagating incoherent plane waves along dimer's axis. The consists of dipolar, electric-magnetic coupling interactions. combined e...

We demonstrate that the trapped magnetic resonance mode can be induced in an asymmetric double-bar structure for electromagnetic waves normally incident onto the double-bar plane, which mode otherwise cannot be excited if the double bars are equal in length. By adjusting the structural geometry, the trapped magnetic resonance becomes transparent with little resonance absorption when it happens ...

The flexoelectric effect for pear-shaped molecules was studied within NPT Monte Carlo simulations. The asymmetric molecules were modelled by a heterogenic two-site pair potential consisting of rigidly connected Gay-Berne and Lennard-Jones particles, thus giving rise to a steric dipolar moment. The simulation data for order parameters and pair correlation functions were used within a density fun...

Molecular function is often predicated on excursions between ground states and higher energy conformers that can play important roles in ligand binding, molecular recognition, enzyme catalysis, and protein folding. The tools of structural biology enable a detailed characterization of ground state structure and dynamics; however, studies of excited state conformations are more difficult because ...

Aseries of uni- and multidimensional variants of the dipolar exchange-assisted recoupling (DEAR) NMR experiment is described and applied to determinations of (13)C-(14)N dipolar local field spectra in amino acids and dipeptides. The DEAR protocol recouples nearby nuclei by relying on differences in their relative rates of longitudinal relaxation, and has the potential to give quantitative geome...

We numerically study the breathing dynamics induced by collision between bright solitons in one-dimensional Bose-Einstein condensates with strong dipole-dipole interaction. This phenomenon is closely related to after-collision short-lived attraction of dipolar effect. The initial phase difference leads asymmetric after collision, which manifested on their different amplitude, frequency, and ato...