Since their discovery, cyclodextrins have widely been used as green and easily available alternatives to promoters or catalysts of different chemical reactions in water. This review covers the research and application of cyclodextrins and their derivatives in asymmetric and stereospecific syntheses, with their division into three main groups: (1) cyclodextrins promoting asymmetric and stereospe...

The pivotal role played by ω-transaminases (ω-TAs) in the synthesis of chiral amines used as building blocks for drugs and pharmaceuticals is widely recognized. However, bulky are challenging to produce. Herein, a ω-TA (TR8) from marine bacterium was synthesize fluorine amine ketone. An analysis reaction conditions process development showed that isopropylamine concentrations above 75 mM had an...