For the first time three different natural compounds, isolated from hairy roots of Astragalus membranaceus, cultivated in airlift bioreactor were tested for their cytotoxic potential and apoptosis induction in a panel of human tumor cell lines. Root cultures, cultivated in bioreactor gave 18.5 g l(-1) dry wt roots with the highest astragaloside production in vitro up to now - 1.64% (astragalosi...

Astragalus mongholicus Bunge has long been used to treat cardiovascular disease in Chinese traditional medicine. However, its mechanisms are not fully understood. In this study, we explored potential mechanisms and protective effects of total flavonoids of Astragalus (TFA) on cardiovascular disease using in vitro experiments and diet-induced atherosclerotic rabbits. We identified six components...

As known from the literature, machine learning (ML) is one of popular researches have been used variable areas. In this work, a novel exemplar pyramid method presented to accurately classify Astragalus L. taxa by using their chromosome images. To implement ML biological images, proposed used. Histogram Oriented Gradients (HOG) utilized as feature generator. The consists preprocessing, generatio...

This study carried out for determination and discrimination of intraspecific diversity of Astragalus verus and Astragalus glaucops by Eco-phytosociological method from west of Iran. In this order, application of Endogenous milieu (special station) for data collecting and then their analyzing permit us only determine existence of inter and intraspecific diversity. Then for determinating kind and...

Radix Astragali has been an important traditional Chinese herbal medicine for over 2000 years. It is derived from two plant species, namely, Astragalus mongholicus [Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao] and Astragalus membranaceus [Astragalus membranaceus (Fisch.) Bge.] (Leguminosae), according to the Pharmacopoeia of the People’s Republic of China. In this study,...