نتایج جستجو برای: associated lipocalin protein

تعداد نتایج: 2522999  

2014
Sukhwinder Kaur Neil Sharma Shiv Ram Krishn Imay Lakshmanan Satyanarayana Rachagani Michael J. Baine Lynette M. Smith Subodh M. Lele Aaron R. Sasson Sushovan Guha Kavita Mallya Judy M. Anderson Michael A. Hollingsworth Surinder K. Batra

Purpose:MUC4 shows aberrant expression in early pancreatic lesions and ahigh specificity for pancreatic cancer. It thushas ahighpotential tobe a sensitive and specific biomarker.Unfortunately, its low serum level limits its diagnostic/prognostic potential.We here report that amultifaceted acute phase protein lipocalin 2, regulated by MUC4, could be a potential diagnostic/prognostic marker for p...

Journal: :Evolution & development 2004
Anna Williford Barbara Stay Debashish Bhattacharya

Cockroach species show different degrees of maternal contribution to the developing offspring. In this study, we identify a multigene family that encodes water-soluble proteins that are a major component of nutritive "Milk" in the cockroach, Diploptera punctata. This gene family is associated with the evolution of a new trait, viviparity, in which the offspring receive nutrition during the gest...

Journal: :Journal of neuroendocrinology 2013
N Hamzic A Blomqvist C Nilsberth

Interleukin (IL)-6 is critical for the febrile response to peripheral immune challenge. However, the mechanism by which IL-6 enables fever is still unknown. To characterise the IL-6-dependent fever generating pathway, we used microarray analysis to identify differentially expressed genes in the brain of lipopolysaccharide (LPS)-treated IL-6 wild-type and knockout mice. Mice lacking IL-6 display...

2014
Sukhwinder Kaur Neil Sharma Shiv Ram Krishn Imay Lakshmanan Satyanarayana Rachagani Michael J. Baine Lynette M. Smith Subodh M. Lele Aaron R. Sasson Sushovan Guha Kavita Mallya Judy M. Anderson Michael A. Hollingsworth Surinder K. Batra

Purpose:MUC4 shows aberrant expression in early pancreatic lesions and ahigh specificity for pancreatic cancer. It thus has ahighpotential tobe a sensitive and specific biomarker.Unfortunately, its low serum level limits its diagnostic/prognostic potential.We here report that amultifaceted acute phase protein lipocalin 2, regulated by MUC4, could be a potential diagnostic/prognostic marker for ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Sukhwinder Kaur Neil Sharma Shiv Ram Krishn Imay Lakshmanan Satyanarayana Rachagani Michael J Baine Lynette M Smith Subodh M Lele Aaron R Sasson Sushovan Guha Kavita Mallya Judy M Anderson Michael A Hollingsworth Surinder K Batra

PURPOSE MUC4 shows aberrant expression in early pancreatic lesions and a high specificity for pancreatic cancer. It thus has a high potential to be a sensitive and specific biomarker. Unfortunately, its low serum level limits its diagnostic/prognostic potential. We here report that a multifaceted acute phase protein lipocalin 2, regulated by MUC4, could be a potential diagnostic/prognostic mark...

2010
Kala Jessie Wei Wei Pang Zubaidah Haji Abdul Rahim Onn Haji Hashim

A gel-based proteomics approach was used to screen for proteins of differential abundance between the saliva of smokers and those who had never smoked. Subjecting precipitated proteins from whole human saliva of healthy non-smokers to two-dimensional electrophoresis (2-DE) generated typical profiles comprising more than 50 proteins. While 35 of the proteins were previously established by other ...

Journal: :Mediators of Inflammation 1999
P Jönsson M L Ståhl K Ohlsson

Extracorporeal circulation (ECC) used during cardiac surgery causes activation of several inflammatory systems. These events are not fully understood but are responsible for complications during the immediate postoperative period. Neutrophil gelatinase-associated lipocalin (NGAL), a member of the expanding lipocalin family, has recently been described as an inflammatory protein. In this study, ...

Journal: :JSLS : Journal of the Society of Laparoendoscopic Surgeons 2017

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