Objective: An assay method was developed and validated for the simultaneous estimation of Lercanipine HCl atenolol using RP-HPLC. Methods: effective chromatographic separation achieved waters symmetry C18 column dimensions 150x4.6 mm, 3.5 μm, as a stationary phase. 0.1 percent ortho phosphoric acid acetonitrile in 50:50 v/v used mobile process with rate flow 1 ml/min UV detection carried out at...

High-performance liquid chromatography (HPLC) with UV, circular dichroism (CD) and intrinsic fluorescence detection was applied to monitor conformational properties of recombinant human interferon alpha2b when performing size exclusion chromatography (SEC) and reversed-phase HPLC (RP-HPLC). In this way native conditions during SEC and structural changes of the protein during RP-HPLC were demons...

background and purpose: gastric cancer (gc) is one of the most common cancers worldwide and in iran. as conventional therapies such as surgery and chemotherapy are invasive with adverse effects, current studies are important as they are conducted to find natural compounds with few adverse effects. in this study, melittin with 26 amino acids was isolated and purified from bee venom and its effec...