This paper is covering new, simplistic method of obtaining the system for controlled delivery of the ascorbic acid. Copolymer poly (D,L-lactide-co-glycolide) (DLPLG) nanoparticles are produced using physical method with solvent/nonsolvent systems where obtained solutions were centrifuged. The encapsulation of the ascorbic acid in the polymer matrix is performed by homogenization of water and or...

Treatment of cultured smooth muscle cells with ascorbic acid resulted in an accumulation of tropoelastin in the culture medium in dose-dependent and exposure time-dependent manner under the condition in which collagen synthesis was stimulated 2-fold. The steady-state level of elastin mRNA was essentially unchanged, whereas collagen mRNA content increased 2-fold by ascorbic acid treatment. Newly...

Concentration of ascorbic acid was determined in different parts of buffalo ovary at four different stages of oestrous cycle viz. early luteal, mid luteal, late luteal and follicular. The stages were decided from the physical and morphological examinations of corpora lutea. The ovary was dissected in three components viz. corpus luteum, follicular fluid and ovarian stromal tissue for ascorbic a...

A new method for the determination of ascorbic, dehydroascorbic and 2.3-diketogulonic acids in animal tissues, blood and urine is described. The material for analysis is homogenized in the presence of stannous chloride in trichloracetic acid and the extract is divided into three aliquots: in one part the ascorbic acid is converted into dehydroascorbic acid by oxidation with bromine water, in th...

Baroreceptor reflex is an important system for neural control of blood pressure. Recently, reactive oxygen species (ROS) have been shown to play an important role in neuronal activity of central areas related to blood pressure control. The aim of this study was to investigate the effects elicited by ascorbic acid (AAC) and N-acetylcysteine (NAC) injections into the 4thV on the parasympathetic c...

In this study some selected chemical properties such as total soluble solids, pH, total acidity, formalin index,  reduced sugar content and ascorbic acid of major sour cherry cultivated grown in different provinces of Iran corresponding were investigated.  Minerals K+, Na+, Ca2+, Mg2+, Cu2+, Fe2+ and Zn2+ were determined by graphite furnace atomic absorption spectrophotometer. The result showed...

Ascorbic acid of fresh fruits and vegetables was extracted with 6% metaphosphoric acid and determined effectively by using a Clg cartridge in a radial compression module and 1.5% NH4H2PO4 mobile phase in a high performance liquid chromatograph. The commonly used AOAC method (2) of First, fresh fruits and vegetables contain corndetermining ascorbic acid content in fresh pounds other than ascorbi...

A well-established protocol to increase the intracellular content of ascorbic acid was used to investigate the effects of the vitamin on DNA single-strand breakage and toxicity mediated by authentic peroxynitrite (ONOO(-)) in U937 cells. This protocol involved exposure for 60 min to 100 microM dehydroascorbic acid, which was taken up by the cells and converted into ascorbic acid via a GSH-indep...

In this study some selected chemical properties such as total soluble solids, pH, total acidity, formalin index, reduced sugar content and ascorbic acid of major sour cherry cultivated grown in different provinces of Iran corresponding were investigated.  Minerals K+, Na+, Ca2+, Mg2+, Cu2+, Fe2+ and Zn2+ were determine...