matic vein was achieved either by partial ligation ofthe left renal vein in rats and dogs or by surgical destruction of the valve of the left testicular vein in a second group of dogs. 1 mo after partial ligation in the rats and 3 mo after partial ligation or valve destruction in the dogs, testicular blood flow was measured using Strontium 85 (SR-85)-labeled microspheres (15±1.1 ,um). Intratest...

The objective of the current study was to extend previous observations and examine the expression pattern and effects of transforming growth factor alpha (TGFalpha) and epidermal growth factor receptor (EGFR) on embryonic testis morphogenesis and growth. The expression of TGFalpha was determined after morphological sex determination (seminiferous cord formation at embryonic day 13 [ED13]) throu...

Cancer-testis antigens are tumor antigens that their expression is almost limited to male germ cells in the testis. Some of cancer-testis antigens are also expressed in the ovary and in trophoblasts. Recently their expression has been seen in different types of tumors. Many pathophysiologic studies suggest that a blood-testis barrier exists in the testis. Because spermatogenesis begins at puber...

PICK1 (protein interacting with C-kinase 1) is a peripheral membrane protein with high expression in brain, testis, pancreas and other neuroendocrine tissues. Male Pick1 knockout mice are completely infertile, with a phenotype resembling the human disease globozoospermia. Since PICK1 is expressed in both testis and neuroendocrine tissues, infertility of Pick1 knockout mice may be due to either ...

aortopulmonary window (apw) is a rare congenital malformation. it results from an incomplete division between the ascending aorta and the pulmonary artery. we describe a 26-year-old male, who presented with a grade ii exertional dyspnea and palpitations. echocardiography revealed an apw with an ascending aorta aneurysm. he underwent surgery under cardiopulmonary bypass without aortic cross-clam...

OBJECTIVE Laparoscopy has become one of the important diagnostic modalities of nonpalpable testis and has been developed and applied in the treatment of this disease. In the present study, we investigated the usefulness of laparoscopy in the diagnosis and treatment of nonpalpable testis. METHODS Laparoscopy was carried out under general anesthesia on 21 patients (23 testes) from October 1991 ...

Testis torsion in pediatric patients is a surgical emergency that requires immediate operative intervention. Heterogeneity, which has been associated with testis loss, is only grossly detected on grayscale ultrasound. To quantify the extent of heterogeneity associated with torsion, we employed a unique, noninvasive technique to determine Dynamic Range (DR) in ultrasound images, and then compare...

objective(s):cyclophosphamide (cp) toxicity on testis was hampered by squid ink polysaccharide (sip) via restoration of antioxidant ability in our previous investigations. this study investigated roles of nrf2/are signal pathway in testis of treated mice. materials and methods: male kunming mice were employed to undergo treatment with sip and/or cp. protein levels of nrf2, keap-1, histone deace...

THE EFFECT OF ALOE VERA HYDROALCOHOLIC EXTRACT ON SPERMATOGENESIS PARAMETERS AND HISTOLOGICAL CHANGES IN TESTIS RATS FED WITH A HIGH-FAT DIET

Protective and synergistic effects of vitamin E selenium against tissue oxidative damages induced by cypermethrin in the rat’s testis