نتایج جستجو برای: as3mt gene

تعداد نتایج: 1141406  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس 1381

ماکروفاژها از سلولهای مهم سیستم ایمنی در پاسخ به عوامل بیماریزای مختلف از جمله ویروس هرپس سیمپلکس یک 1- ‏‎hsv0 هستند و عوامل موثر بر فعالیت آنها می توانند در سرنوشت بیماری موثر باشند. در این مطالعه اثر نوروپپتیدهای ‏‎substance p(sp)‎‏ و‏‎calcitonin gene related-peptide‎‏ (‏‎cgrp‎‏) که تحت شرایطی مثل استرس و التهاب از رشته های عصبی حسی آزاد می شوند و دارای گیرنده فعال بر روی ماکروفاژها می باشند ...

Journal: :genetics in the 3rd millennium 0
abolfazl barzegari alireza ostadrahimi vahideh ebrahimzadeh attari abolfazl gorbani

in view of the fundamental role of genetics in development of obesity, the present study aimed to investigate the single nucleotide polymorphism of some obesity-related genes among a subset of obese women living in tabriz, iran. for this purpose, 70 eligible obese women (aged 18-45 years) were genotyped for the uncoupling protein-1 (ucp-1) -3826a>g, ß3-adrenergic receptor (ß3adr) trp64arg, lept...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2016
Rick J Jansen Maria Argos Lin Tong Jiabei Li Muhammad Rakibuz-Zaman Md Tariqul Islam Vesna Slavkovich Alauddin Ahmed Ana Navas-Acien Faruque Parvez Yu Chen Mary V Gamble Joseph H Graziano Brandon L Pierce Habibul Ahsan

BACKGROUND Exposure to inorganic arsenic (iAs), a class I carcinogen, affects several hundred million people worldwide. Once absorbed, iAs is converted to monomethylated (MMA) and then dimethylated forms (DMA), with methylation facilitating urinary excretion. The abundance of each species in urine relative to their sum (iAs%, MMA%, and DMA%) varies across individuals, reflecting differences in ...

2017
Islam Khairul Qian Qian Wang Yu Han Jiang Chao Wang Hua Naranmandura

A variety of studies indicated that inorganic arsenic and its methylated metabolites have paradoxical effects, namely, carcinogenic and anticancer effects. Epidemiological studies have shown that long term exposure to arsenic can increase the risk of cancers of lung, skin or bladder in man, which is probably associated with the arsenic metabolism. In fact, the enzymatic conversion of inorganic ...

Journal: :Toxicology and applied pharmacology 2010
Tetsuro Agusa Hisato Iwata Junko Fujihara Takashi Kunito Haruo Takeshita Tu Binh Minh Pham Thi Kim Trang Pham Hung Viet Shinsuke Tanabe

To elucidate the role of genetic factors in arsenic metabolism, we investigated associations of genetic polymorphisms in the members of glutathione S-transferase (GST) superfamily with the arsenic concentrations in hair and urine, and urinary arsenic profile in residents in the Red River Delta, Vietnam. Genotyping was conducted for GST omega1 (GSTO1) Ala140Asp, Glu155del, Glu208Lys, Thr217Asn, ...

Journal: :medical journal of islamic republic of iran 0
amir mehrgou department of medical genetics and molecular biology, school of medicine, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) mansoureh akouchekian department of medical genetics and molecular biology, school of medicine, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

many factors including genetic, environmental, and acquired are involved in breast cancer development across various societies. among all of these factors in families with a history of breast cancer throughout several generations, genetics, like predisposing genes to develop this disease, should be considered more. early detection of mutation carriers in these genes, in turn, can play an import...

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