نتایج جستجو برای: aryltetralin lignans

تعداد نتایج: 1608  

Journal: :Nutrition and cancer 2005
Karen D Coulman Zhen Liu Winston Quan Hum John Michaelides Lilian U Thompson

The mammalian lignans enterolactone and enterodiol, which are produced by the microflora in the colon of humans and animals from precursors in foods, have been suggested to have potential anticancer effects. This study determined the production of mammalian lignans from precursors in food bars containing 25 g unground whole flaxseed (FB), sesame seed (SB), or their combination (FSB; 12.5 g each...

2016
Esther Molina‐Montes María‐José Sánchez Raul Zamora‐Ros H.B(as) Bueno‐de‐Mesquita Petra A. Wark Mireia Obon‐Santacana Tilman Kühn Verena Katzke Ruth C. Travis Weimin Ye Malin Sund Alessio Naccarati Amalia Mattiello Vittorio Krogh Caterina Martorana Giovanna Masala Pilar Amiano José‐María Huerta Aurelio Barricarte José‐Ramón Quirós Elisabete Weiderpass Lene Angell Åsli Guri Skeie Ulrika Ericson Emily Sonestedt Petra H. Peeters Isabelle Romieu Augustin Scalbert Kim Overvad Matthias Clemens Heiner Boeing Antonia Trichopoulou Eleni Peppa Pavlos Vidalis Kay‐Tee Khaw Nick Wareham Anja Olsen Anne Tjønneland Marie‐Christine Boutroun‐Rualt Françoise Clavel‐Chapelon Amanda J. Cross Yunxia Lu Elio Riboli Eric J. Duell

Despite the potential cancer preventive effects of flavonoids and lignans, their ability to reduce pancreatic cancer risk has not been demonstrated in epidemiological studies. Our aim was to examine the association between dietary intakes of flavonoids and lignans and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. A total of 865 exocrin...

2017
Beatrice A Boucher Susitha Wanigaratne Shelley A Harris Michelle Cotterchio

2 Background: Isoflavones and lignans (phytoestrogens) are dietary components with potential 3 anti-carcinogenic effects. Although the intake of isoflavones and lignans may affect breast 4 cancer treatment and prognosis – and associations may differ by menopausal status post5 diagnosis intake data are limited. 6 Objective: We aimed to describe post-diagnosis isoflavone and lignan intake in newl...

2001
JIM-MIN FANG CHING-KUO LEE

Umbelliferone, 13 lignans and an unusual compound 2-(3,4-methylenedioxyphenyl)propane-1,3-diol, were isolated from the leaves of Juniperus chinensis. The lignans include meso-secoisolariciresinol, 3,4-methylenedioxy-3’,4’dimethoxylignan-9’,9-olide, hibalactone, isohibalactone, 7-oxohinokinin, 7-hydroxyhinokinin, 7-acetyloxyhinokinin, (+ )-xanthoxylol, dihydrodehydrodiconiferyl alcohol, 3-methox...

2013
Cristiano Côrtes Daniele da Silva-Kazama Ricardo Kazama Chaouki Benchaar Geraldo dos Santos Lucia M. Zeoula N. Gagnon Hélène V. Petit

Ruminal microbiota plays an important role in the conversion of plant lignans into mammalian lignans. The main mammalian lignan present in the milk of dairy cows fed flax products is enterolactone (EL). The objectives of the present study were to investigate the effects of abomasal infusion of flax oil on the metabolism of flax lignans and concentrations of EL in biological fluids of dairy cows...

Journal: :Plant & cell physiology 2009
Hyun Jung Kim Eiichiro Ono Kinuyo Morimoto Tohru Yamagaki Atsushi Okazawa Akio Kobayashi Honoo Satake

Lignans are a large class of secondary metabolites in plants, with numerous biological effects in mammals, including antitumor and antioxidant activities. Sesamin, the most abundant furofuran-class lignan in sesame seeds (Sesamum plants), is produced by the cytochrome P450 enzyme CYP81Q1 from the precursor lignan, pinoresinol. In contrast, Forsythia plants produce dibenzylbutyrolactone-class li...

2011
A.R. Gohari S Saeidnia M Bayati-Moghadam Gh Amin

BACKGROUND AND THE PURPOSE OF THE STUDY Stelleropsis antoninae Pobed. (Family: Thymelaeaceae) grows wildly as an herbaceous plant in Iran. Most of the Thymelaeaceous plants contain lignans and neolignans, which have important pharmacologically properties. In the present study, the isolation and identification of the main lignans and neolignans of S. antoninae, which has not been previously repo...

Journal: :Antimicrobial agents and chemotherapy 2007
Valter F de Andrade-Neto Tito da Silva Lucia M Xavier Lopes Virgílio E do Rosário Fernando de Pilla Varotti Antoniana U Krettli

Extracts from Holostylis reniformis were tested in vivo against Plasmodium berghei and in vitro against a chloroquine-resistant strain of Plasmodium falciparum. The hexane extract of the roots was the most active, causing 67% reduction of parasitemia in vivo. From this extract, six lignans, including a new (7'R,8S,8'S)-3',4'-methylenedioxy-4,5-dimethoxy-2,7'-cyclolignan-7-one, were isolated and...

Journal: :The British journal of nutrition 2014
Yulan Lin Agneta Yngve Jesper Lagergren Yunxia Lu

Dietary lignans, quercetin and resveratrol have oestrogenic properties, and animal studies suggest that they synergistically decrease cancer risk. A protective effect of lignans on the development of oesophageal cancer in humans has recently been demonstrated, and the present study aimed to test whether these three phytochemicals synergistically decrease the risk of oesophageal cancer. Data fro...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Malin Bergman Jungeström Lilian U Thompson Charlotta Dabrosin

PURPOSE Vascular endothelial growth factor (VEGF) is a potent stimulator of angiogenesis, which is crucial in cancer progression. We have previously shown that estradiol (E2) increases VEGF in breast cancer. Phytoestrogens are potential compounds in breast cancer prevention and treatment by poorly understood mechanisms. The main phytoestrogens in Western diet are lignans, and flaxseed is a rich...

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