Regarding the increasing numbers of IV drug addicts, the incidence of infected pseudoaneurysm is increasing. So far, different therapeutic strategies have been tried, but each method has its own drawbacks. Therefore, discovering an appropriate therapeutic method is necessary. 65 patients with infected pseudoaneurysm due to drug injection referred to Shohada Medical Center from Feb 1994 til...

Objectives: Although venography guidance is helpful for central venous catheter placement, it is sometimes difficult to place a peripheral intravenous cannula for enhancement. We designed a new technique for establishing femoral venous access using venography guidance in the return phase of peripheral arteriography. This new technique was named arterial injection venous return guidance. Here we...

Purpose Current intra-arterial chemotherapy (IAC) drug regimens for retinoblastoma have ocular and vascular toxicities. No small-animal model of IAC exists to test drug efficacy and toxicity in vivo for IAC drug discovery. The purpose of this study was to develop a small-animal model of IAC and to analyze the ocular tissue penetration, distribution, pharmacokinetics, and treatment efficacy. M...

Context The selective arterial secretagogue injection test is a functional examination to determine localization of functional neuroendocrine tumor. Since the selective arterial secretagogue injection test capitalizes on the hormone-secreting ability of neuroendocrine tumor, no reports on this test in non-functional neuroendocrine tumors have yet been published. Objective In this study, we eval...

Basilar Arterial Flow Changes Elicited by Hydralazine Hydrochloride, Isoxsuprine Hydrochloride and Nylidrin Hydrochloride • The influence of infusion of hydralazine, isoxsuprine or nylidrin on blood flow in the basilar artery and on systemic blood pressure was investigated in anesthetized dogs. The drugs were administered individually in 1-mg and 2-mg doses and in various combinations of 1 mg e...

Correspondence to Professor Jean-Denis Laredo; [email protected] The Food and Drug Administration (FDA) has not approved any injectable glucocorticoid product for epidural administration, but epidural injection of glucocorticoids is commonly used to manage radicular neck and back pain. Severe and sometimes fatal neurological events have occurred immediately after epidural injection of g...

To investigate the channels and neurotransmitters in the ventrolateral medulla (VLM) oblongata that are responsible for the maintenance of sympathetic tone and cardio-respiratory reflex regulation. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM), calcium channel blockers, agonists and antagonists were made throughout the VLM in anaesthetized rats. Arterial blood pressure, sym...

abstract background: providing better surgical conditions with meticulous control of intraocular pressure (iop) is one of the most important factors that affect the success rate in ophthalmic surgery. clonidine is a selective central α2 agonist with analgesic, antianxiety and sedative effects which makes it a good choice in premedication recently. in this study, we compared the effects of oral ...