the effects of methanolic extract and leaf powder of artemisia annua were studied on performance, cellular and humoral immunity in 240 cobb broiler chicks in a completely randomized design. control group did not receive any treatment. the chicks in the second and third groups were fed with feed which contained 2000 and 4000 ppm plant extract in diet and in the groups 4, 5 and 6 chicks received ...

Submit Manuscript | http://medcraveonline.com could be evidenced for these drugs. Willcox is right in stating that no large scale, randomized, double blind clinical trials confirming the efficiency of Artemisia plants against malaria are available. Indeed, they are forbidden by WHO. Only clinical trials with ACTs have been run in high numbers. OXFAM and others even claim that Africans are guine...

Abstract Nanoparticles are known bio elicitors in plant biotechnology. Different concentrations of ZnO, CuO and CoO nanoparticles were used for the enhanced accumulation secondary metabolites antioxidant activities callus derived from root, shoot leaf Artemisia annua L. Biomass was somehow affected on high Nps. Phenolic content observed maximum (60µg) at 0.1mg/l CuONps. Total activity (33µg) ro...

Artemisia annua L. (Asteraceae) is native to China, now naturalised in many other countries, well known as the source of the unique sesquiterpene endoperoxide lactone artemisinin, and used in the treatment of the chloroquine-resistant and cerebral malaria. The essential oil is rich in mono- and sesquiterpenes and represents a by-product with medicinal properties. Besides significant variations ...

Despite the importance of Artemisia annua L. as the only source of the anti-parasitic drug artemisinin, little is known on the effects of biotic and abiotic stress on artemisinin accumulation. Water deficit is the most limiting factor on plant growth, however it can trigger secondary metabolite accumulation, depending on the plant growth stage and intensity. A. annua cultivated in growth chambe...

Most TPSs (terpene synthases) contain plasticity residues that are responsible for diversified terpene products and functional evolution, which provide a potential for improving catalytic efficiency. Artemisinin, a sesquiterpene lactone from Artemisia annua L., is widely used for malaria treatment and progress has been made in engineering the production of artemisinin or its precursors. In the ...

BACKGROUND Artemisia annua L. has been used for many centuries in Chinese traditional medicine. Artemisinin, the active principle was first isolated and identified in the 1970s becoming the global back bone to the fight against malaria. Our research group previously developed an economic and ecological friendly process to obtain this compound. In the pursuit to also exploit the residue generate...

Artemisinin is extracted from a traditional Chinese medicinal herb Artemisia annua L., which is regarded as the most efficient drug against malaria in the world. In recent years, attention has been paid to increase the artemisinin content through transgenic methods because of the low content of artemisinin in wild plants. In this article, three functional artemisinin-related genes namely dxr, c...

[This corrects the article on p. 626 in vol. 5, PMID: 25505453.].

The antimalarial artemisinin, the active principle of the plant Artemisia annua L., was extracted by Supercritical Fluid Extraction (SFE). Soxhlet extraction was studied as comparison processes. The extracts were analyzed by the indirect method GC-FID. The maximal extraction yield (1.82%DW) was obtained by SFE at T=40°C, P=200bar, CO2flow=4.5g/min, and 20% ethanol as modifier. The artemisinin e...