Substituted Schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (Ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. On cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds ...

We report a novel luminescent Al-based metal-organic gel G1 comprising 1,4,5,8-triptycenetetracarboxylic acid, which exhibits highly sensitive detection towards nitro aromatic compounds particularly picric acid. Furthermore, under identical reaction conditions, using a Co(II) salt instead, a novel 3D framework material, trip-MOF-1, was isolated and its sensitivity towards picric acid was also e...

A database of mutagenicity test results of new chemicals has been developed. Based on the amendment of the Industrial Safety and Health Law (ISHL) in 1979, manufacturers and importers in Japan are required to register any new work place chemicals with bacterial mutagenicity test results. At present more than ten thousand substances have been examined. We have surveyed correlations between 44 su...

The ability of 51 compounds, of known carcinogenic potential, to induce "unscheduled DNA synthesis" in HeLa cells has been tested in the presence or absence of a rat liver mixed-function oxidase preparation. Chemicals tested included those giving erroneous results in bacterial mutagenicity assays as well as representative compounds from various classes of chemical carcinogens including nitrosam...

Abstract. Nitro-aromatic compounds (NACs) were measured hourly at a rural site in China during wintertime to monitor the changes due local and regional impacts of biomass burning (BB). Concurrent continuous measurements concentrations 16 NACs gas particle phases performed with time-of-flight chemical ionization mass spectrometer (CIMS) equipped Filter Inlet for Gases AEROsols (FIGAERO) unit usi...