Aquaporin-4, the major water-selective channel in astroglia throughout the central nervous system, facilitates water movement into and out of the brain. Here, we identify a novel role for aquaporin-4 in astroglial cell migration, as occurs during glial scar formation. Astroglia cultured from the neocortex of aquaporin-4-null mice had similar morphology, proliferation and adhesion, but markedly ...

It has previously been shown that hydraulic conductance in bur oak leaves (Quercus macrocarpa Michx.), measured with the high pressure flow meter technique (HPFM), can significantly increase within 30 min following exposure to high irradiance. The present study investigated whether this increase could be explained by an increase in the cell-to-cell pathway and whether the response is linked to ...

Aquaporin-4 is a transmembrane water channel protein, the C-terminal domain of which facing cytosol. In process investigating role aquaporin-4 with regard to intracellular trafficking, we observed that derivative aquaporin-4, in 53 amino acids had been removed (?271-323), was localized compartments, including endoplasmic reticulum, but not expressed on plasma membranes. This determined by immun...

In this study, we have investigated the expression of aquaporin 4 during blood-brain barrier development in the optic tectum of chick embryos and newly hatched chicks, by means of western-blot, reverse transcriptase-polymerase chain reaction, immunohistochemistry, and freeze-fracture and high-resolution immunogold electron microscopy. In the optic tecta of day-14 embryos, western blot analysis ...

OBJECTIVES The purpose of this study is to identify and compare the presence and location of aquaporins in the fetal and adult larynx using immunohistochemical techniques. METHODS Immunohistochemical staining was performed on adult and fetal true vocal fold specimens. The presence and location of aquaporins -1, -2 and -3 in the fetal specimens were then compared to the adult specimens. RESU...