Biosynthesis of Silver Nanoparticles Using Hydroethanolic Extract Cucurbita pepo L. Fruit and Their Anti-proliferative Apoptotic Activity Against Breast Cancer Cell Line (MCF-7)

the pathogenesis of equine grass sickness (egs) has not fully understood. a better understanding of the exact pathogenesis of diseases can help to make an accurate diagnosis. previous studies reported some pathological damage of neuronal cells in egs patients. in this study, primarily cytotoxicity of serum from three clinically egs-diagnosed horses on pc12 tet-off (pto) cells was assessed. subs...

background: microtubules (mt) are important components of cell cytoskeleton and play key roles in cell motility mitosis and meiosis. they are also the targets of several anticancer agents which indicating their importance in maintaining cell viability. microtubular reorganization contributing to apoptotic morphology occurs in normal and neoplastic cells undergoing apoptosis induced by cytotoxic...

background and objective: garlic has been known worldwide as a dietary constituent with many pharmacological effects. the present in vitro study was designed to investigate the putative anticancer effect of garlic extract on cancer cells, and if this effect was through apoptosis induction. material and methods:  human colon adenocarcinoma cells ht29 were treated with different doses (1, 5 and 1...

background: the mitogen-activated protein kinase (mapk) pathway is one of the major signaling pathways that transmit intracellular signals initiated by extracellular stimuli to the nucleus. the stress-activated protein kinase (sapk)/c-jun nh2-terminal kinase is a subfamily of map kinases implicated in cytokine and stress responses. objective: in this study, we have examined total and phosphoryl...