At present two prophylactic human papilloma virus (HPV) vaccines are commercially available. The tetravalent vaccine comprised of four VPH types (6, 11, 16, and 18) distributed in the national program in Colombia and the bivalent vaccine comprised of VPH types 16 and 18, respectively. Types 16 and 18 are accountable for 70% of cervical cancer, most vulva, vagina, penis, anus and one third of or...

Background: The gold standard of the management of rectal cancer in the middle and lower parts is low anterior resection with coloanal anastomosis. About 50% of the patients undergoing this procedure might experience some complications because of the low capacity of the neorectum. The aim of this study was to evaluate ileal J-pouch interposition as a neorectum between the anal canal and the rem...

In April 2009, The Lancet Oncology published the findings of a working group (36 scientists from 16 countries) that met in February 2009 at the International Agency for Research on Cancer (Lyon, France) to reassess the carcinogenicity of the biological agents classified as “carcinogenic to humans” (group 1) [1]. With regard to human immunodeficiency virus (HIV) infection, a clear link has been ...

Abstract Endoscopic submucosal dissection enables en bloc resection of large superficial colorectal neoplasms. However, it is sometimes challenging to retrieve a resected specimen via the anus without sample fragmentation. A novel “bag-type” retrieval device has been developed accomplish complete isolation and non-destructive delivery oversized specimens. This single-center retrospective study ...

UNLABELLED Study Type - Prognosis (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? In animals, anogenital distance has been shown to be related to the action of fetal androgens, and exposure to chemicals such as dioxins that exhibit antiandrogenic activity results in shorter distances in male rats. In studies conducted in children, anogenital distance has ...

Cervical cancer is one of the commonest cancers of the female anogenital tract and a leading cause of morbidity and mortality. The association of HPV and cervical cancer was first suggested by zur Hausen in 1976.1 It is now believed that 94-100% of cervical cancers as well as tumours of the penis, anus, vagina, and vulva are associated with sexually transmitted genital infection by the human pa...