Deficiencies of Selenium (Se) is correlated with the risk and onset autoimmune thyroid disease (AITD). The aim this study was to determine association between Se supplementation AITD. Methods: Electronic data searches 4 databases were performed. We assessed included studies using PRISMA for protocol assurance. Five met our inclusion criteria analyzed. predictor covariate in present administrati...

PURPOSE Selenium is an essential trace mineral and a component of selenoproteins that are involved in the production of thyroid hormones and in regulating the immune response. We aimed to explore the effect of low-dose selenium supplementation on thyroid peroxidase antibody (TPO-Ab) concentration and thyroid function in pregnant women from a mild-to-moderate iodine-deficient population. METHO...

BACKGROUND Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women in reproductive age. In many cases, PCOS is associated with infertility and increased risk of miscarriage. Recent studies have detected the presence of several organ specific and nonspecific autoantibodies in women with PCOS. OBJECTIVES The aim of this study was to evaluate the prevalence and level...

BACKGROUND Complex bidirectional relationships have been described between body weight, thyroid function, and risk of thyroid disorders, including thyroid autoimmunity. We used a life-course approach to examine the potential association of childhood or adult body weight with the risk of thyroid autoimmunity and other thyroid disorders at age 60-64 years in a large population-based birth cohort ...

Crude thyroid peroxidase extracted from human thyroid microsomes was covalently bound onto polyacrylic and polyfunctional copolymerized microparticles. We observed agglutination of the thyroid peroxidase-microparticle conjugate with 13 monoclonal antibodies (mAbs) specific for epitopes on four different antigenic domains of human thyroid peroxidase (TPO; EC 1.11.1.7), after addition of anti-mou...

Methods: The authors examined 3712 women randomly selected from the general population. Serum was analysed for thyroid peroxidase antibody (TPO-Ab) and thyroglobulin antibodies (Tg-Ab) using assays based on a RIA technique. Data were analysed in logistic regression models to adjust for possible confounders. Women previously treated for thyroid disease or with a pregnancy within one year prior t...

Objective: The clinical diagnosis of autoimmune thyroid diseases (AITD) is usually confirmed by detection of various antibodies in the patient’s blood or by histopathological evaluation. In this study, we evaluated the prevalence of serum antibodies in histopathologically proven AITD and assessed the correlation between antibodies and thyroid dysfunction. Methods: 100 consecutive patients with ...

In moderately iodine-deficient, pregnant, thyroid peroxidase antibody (TPO-Ab)-positive women the role of iodine supplementation in the development of postpartum thyroid dysfunction (PPTD) was studied in a placebo-controlled, randomized, double blind trial. Screening for TPO-Ab was performed in early pregnancy in a population of healthy pregnant Danish women with no previous diagnosed thyroid d...

Calcitonin (CT) is an important clinical marker for the diagnosis and follow-up of medullary thyroid carcinoma, although it is not absolutely specific. Some authors have reported C-cell hyperplasia in a number of thyroid specimens affected by Hashimoto's thyroiditis. The association between thyroiditis and hypercalcitoninemia is still controversial because some authors have reported low CT leve...

Aim. The aim of the study was to study the relation of vitiligo with demographic data like age, sex, and duration and determine the prevalence of thyroid autoimmunity in vitiligo patients. Materials and Methods. This study was a cross sectional study consisting of 100 patients clinically diagnosed (old and new) as having vitiligo irrespective of age or sex. Patients with known thyroid disease o...