Purpose To investigate the effects of Chamaecyparis obtusa (CO) on human corneal epithelial (HCE) cells, a murine experimental dry eye (EDE) model, and the efficacy of antioxidant eye mask in dry eye disease (DED) patients. Methods 0.001%, 0.01%, and 0.1% CO extracts were used to treat HCE cells, cell viability, and production of antioxidative enzymes, and reactive oxygen species (ROS) were a...

Numerous studies have provided information indicating the involvement of oxidative stress in the pathophysiology of depressive disorder (DD). The antioxidative system protects against the effects caused by reactive oxygen species (ROS). Catalase (CAT) is one of antioxidative enzymes observed to change their levels in the course of depression. The enzyme decomposes hydrogen peroxide (H(2)O(2)), ...

background: inclusion of antioxidant sources in feed or water reduces the detrimental effects of free radicals and increases the antioxidative potential and stability of lipids in heat stressed broiler chicken. objectives: this study was conducted to examine the effect of satureja khuzistanica essential oils (skeo) on early postmortem and ultimate ph as well as antioxidative potential of breast...

Sea cucumber is a precious and nutritious food with abundant protein other bioactive compounds, among which sea peptide (SCP) exhibits many beneficial functions. Although research on the development of SCP attracting more attention, ability to translate these new findings into industrial practice products remains immature. This review summarizes production characterization emphasizes recent adv...

Oxidative stress has been implicated in the pathogenesis of many kinds of neurodegenerative disorders, particularly Parkinson's disease. Quercetin is a bioflavonoid found ubiquitously in fruits and vegetables, and has antioxidative activity. However, the underlying mechanism of the antioxidative effect of quercetin in neurodegenerative diseases has not been well explored. Here, we investigated ...

dpph radical-scavenging activity of the bene hull oil (bho), sesame oil (seo), rice bran oil (rbo), the oils' methanolic (ch3oh/h2o, 80:20 v/v) or hexane extracts, and their unsaponifiable matters fraction were measured and compared with each other. as a radical-scavenger, seo was significantly stronger than rbo and bho, respectively. unlike bho and rbo, the unsaponifiable (usm) fraction of the...

This study investigated the antioxidative effect of S-propargyl-cysteine (SPRC) on nonalcoholic fatty liver (NAFLD) by treating mice fed a methionine and choline deficient (MCD) diet with SPRC for four weeks. We found that SPRC significantly reduced hepatic reactive oxygen species (ROS) and methane dicarboxylic aldehyde (MDA) levels. Moreover, SPRC also increased the superoxide dismutase (SOD) ...

In the present study, we examined the effect of schisandrin (SCH) of Schisandra chinensis on the amyloid-beta(1-42)- (Aβ(1-42)-) induced memory impairment in mice and elucidated the possible antioxidative mechanism. Mice were intracerebroventricular (i.c.v.) injected with the aggregated Aβ(1-42) and then treated with SCH (4, 12, and 36 mg/kg body weight) or donepezil (DPZ), a reference drug (0....