Antioxidant activity of fresh Allium sativum L. (garlic) is well known and is mainly due to unstable and irritating organosulphur compounds. Fresh garlic extracted over a prolonged period (up to 20 months) produces odourless aged garlic extract (AGE) containing stable and water soluble organosulphur compounds that prevent oxidative damage by scavenging free radicals. The aim of this study was t...

the study was aimed at evaluating the antioxidant activity of hydroalcoholic solution extracts of urtica dioica l. (ud), malva neglecta wallr. (mn) plants and their mixture. in this study, flower (udf), root (udr), seed (uds) and leaf (udl) parts of ud and flower (mnf) and leaf (mnl) parts of mn were used. the antioxidant properties of hydroalcoholic extracts and their mixture were evaluated us...

Apple polyphenol extract has strong antioxidant activity and various physiological functions, and is used in Japan as a food additive and nutritional supplements. Here, we tested the consumption safety of Applephenon, which is a polyphenol extract produced from unripe apples. The Ames test without S9 mixture revealed that Applephenon, had slight mutagenicity at a high concentration of 2500 micr...

Objective:The present study was designed to evaluate the antioxidant, analgesic, and anti-inflammatory activities ofthe methanolic extract of Piper betle leaves (MPBL). Materials and Methods: MPBL was evaluated for anti-inflammatory activity using carrageenan-induced hind paw edema model. Analgesic activity of MPBL was evaluated by hot plate, writhing, and formalin tests. Total phenolic and fla...

From well-known antioxidants agents, we developed a first pharmacophore model containing four common chemical features: one aromatic ring and three hydrogen bond acceptors. This model served as a template in virtual screening of Maybridge and NCI databases that resulted in selection of sixteen compounds. The selected compounds showed a good antioxidant activity measured by three chemical tests:...

Studies on amino acid composition and antioxidant activities of collagen Polypeptides from the Holothuria nobilis Selenka were carried out in this paper. Results revealed that collagen polypeptides mainly contains glycine(Gly), alanine(Ala), glutamate (Glu), proline (Pro) and hydroxyproline (Hyp) with high medicinal values and good tasting. The rate of delicious amino acid, pharmacodynamics ami...

In the present study, a highly sensitive and simple high-performance liquid chromatographic method was developed and validated for simultaneous determination of three unsaturated fatty acids, αlinolenic acid, linoleic acid and oleic acid in walnut oil. Unsaturated fatty acids were quantified through HPLC using a reversephase C8 column and UV detector. Besides, the antioxidant activity of walnut...

A novel polymeric material with antioxidant properties and suitable for ophthalmic application was synthesized by free radical grafting reaction between 2-hydroxyethyl methacrylate and quercetin. The presence of quercetin in the polymeric chain was confirmed by FT-IR and UV-Vis analyses, while an estimation of the amount of quercetin bound per gram of polymer was obtained by the Folin-Ciocalteu...

CONTEXT Previous studies have shown that Spirulina platensis Gomont (Phormidiaceae) (SP) extract has beneficial effects on many disease conditions. The putative protective effects of SP were investigated in diabetic rats. OBJECTIVE The current study investigates the antioxidant effects of SP in diabetic Wistar rats. MATERIALS AND METHODS Alloxan monohydrate (150 mg/kg body weight) was intra...