Accurate classification of antimicrobial peptides according to their biological activities will facilitate the design of novel antimicrobial agents and the discovery of new therapeutic targets. In this work, an excellent algorithm of Increment of Diversity with Quadratic Discriminant analysis (IDQD) was proposed to classify antimicrobial peptides with diverse biological activities.

Raising public awareness of the need to use antibiotics appropriately is a major focus of the UK Government's strategy to tackle antimicrobial resistance. To investigate the public's views on antibiotic use and resistance we conducted a survey of 120 people as part of patient engagement activities held at University College London Hospital in June 2015.

Antimicrobial resistance is a worldwide threat and a problem with large clinical and economic impact. Antimicrobial Stewardship Programs are a solution to curb resistance development. A problem of resistance is a separation of actions and consequences, financial and clinical. Such a separation makes it difficult to create support among stakeholders leading to a lack of sense of responsibility. ...

Many antimicrobial peptides (AMPs) function by forming various oligomeric structures and/or pores upon binding to bacterial membranes. Because such peptide aggregates are capable of inducing membrane thinning and membrane permeabilization, we expected that AMP binding would also affect the diffusivity or mobility of the lipid molecules in the membrane. Herein, we show that measurements of the d...

Orchis latifolia belonging to the family Orchidaceae is extensively used in traditional Indian medicine against a wide spectrum of ailments including dysentery, diarrhoea, chronic fever, wounds, burns, fractures and general weakness. The present study relates to the bioactive extracts from O. latifolia against multidrug resistant (MDR) bacteria and Candida albicans. Methanolic extract of O. lat...

1. Transfusion medicine. Technical manual, 2nd ed. WHO; 2003. p. 151. 2. Garg S, Mathur DR, Garg DK. Comparison of seropositivity of HIV, HBV, HCV and syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol 2001;44:409-12. 3. Nanu A, Sharma SP, Chatterjee K, Jyoti P. Markers for transfusion transmissible in north Indian voluntary and replacement blood dono...

The present study investigated the effect of sumac (SWE) and Rosemary water extracts (RWE) on microbial growth in ground beef meat during refrigerated storage. The meat samples were explored for changes in TVC, E.coli (0157:H7) and S.aureus populations. Antimicrobial effectiveness of extracts was more pronounced against Gram-positive strain compared with Gram-negative strain. Antimicrobial impa...

The present study investigated the effect of sumac (SWE) and rosemary water extracts (RWE) on microbial growth in ground beef meat during refrigerated storage. The meat samples were explored for changes in TVC, E. coli (0157:H7) and S. aureus populations. Antimicrobial effectiveness of extracts was more pronounced against gram-positive strain compared with gram-negative strain...