Diarrhoea is a major public health problem in developing countries. An estimated 1.3 billion episodes of diarrhoea occur each year. Diarrhoeal diseases cause a heavy economic burden on health services. In developing countries, diarrhoea is almost universally infectious in origin. Appropriate clinical management of diarrhoea includes oral rehydrate therapy and chemotherapy. New Diarex is a formu...

45 children were admitted to hospital after ingesting varying quantities of diphenoxylate (Lomotil). One died and 44 recovered without any sequelae. Four patients were comatose, 32 were drowsy, and 9 suffered respiratory depression. No correlation was found between ingested dose and the severity of symptoms. Because of its action in rendering the gut atonic, removal of diphenoxylate by gastric ...

The 70% hydroethanolic extracts of Calotropis procera (CP) and Calotropis gigantea (CG) leaves have been evaluated and compared for anti-diarrheal activity using castor oil-induced diarrhea model in rats. Results showed statistically significant reduction in the frequency and severity of diarrhoea produced by castor oil in both CP and CG. The anti-diarrheal effect of CP was found superior to CG...

Most of the medicinal agents are originated from nature and considered as a rich source for producing drugs including modern drugs. Swietenia machrophylla is one of the most important plant of the family, Meliaceae. It is planted widely in Southern Asia and in the Pacific region. This review provides information on its traditional uses, phytochemical and medicinal values. The plant extracts and...

the   stembark of mammea africana is used traditionally for the treatment of stomach pains. the present study was designed to evaluate the effects of ethanolic stembark extract of mammea africana on experimentally induced diarrhoea and ulcer . the extract ( 30 – 90mg/kg) was administered orally in rats 30 minutes to one hour before the induction of diarrhoeal and ulcer using different experimen...

The   stembark of Mammea africana is used traditionally for the treatment of stomach pains. The present study was designed to evaluate the effects of ethanolic stembark extract of Mammea africana on experimentally induced diarrhoea and ulcer . The extract ( 30 – 90mg/kg) was administered orally in rats 30 minutes to one hour before the induction of diarrhoeal and ulcer using di...

Plants of genus Polygonatum (Ruscaceae) are widely used in traditional medicine to cure many diseases such as ageing, antioxidative action, insecticidal, antiherpetic, antinociception and aphrodisiac. A variety of phytoconstituents has been isolated from the Polygonatum species which include lignans, flavonoids, coumarins, steroids, terpenes, fatty acids and aliphatic long chain compounds. Anti...

Intervention Participants were allocated to receive 31 days of dietary fibre supplementation with psyllium, 7.1 g/day (n=13), or gum arabic, 25 g/day (n=13); or placebo given as pectin, 0.25 g/day (n=13). Supplementation was mixed into fruit juice and divided into 2 servings for consumption during the morning and evening meals. Participants were instructed to maintain their usual diet, and thos...

Loranthus micranthus Linn. is a medicinal plant from the Loranthaceae family commonly known as an eastern Nigeria species of the African mistletoe and is widely used in folkloric medicine to cure various ailments and diseases. It is semiparasitic plant because of growing on various host trees and shrubs and absorbing mineral nutrition and water from respective host. Hence, the phytochemicals an...