Background. Elaeocarpus serratus L. (Family: Elaeocarpaceae) is a tropical fruit tree, traditionally used in the treatments of poisoning, diarrhea, arthritis, and other diseases. Objectives. The current study was performed to conduct analgesic, antidiarrheal, hypoglycemic activity E. mice model using methanolic bark crude extract. Methods. To assess peripheral central analgesic activity, acetic...

The needs for safe, therapeutically effective antidiarrheal combination continuously lead to effective treatment. When administered simultaneously, metronidazole-kaolin interactions have been reported by FDA but not studied. This paper is the first to study metronidazole-kaolin interactions. Adsorption isotherms of a metronidazole-kaolin antidiarrheal combination from aqueous solutions at an in...

BACKGROUND Hopea Odorata, locally known as Telsur (Bangladesh), has some traditional uses as folk medicine. This study aims to investigate the antioxidant, antidiarrheal, hypoglycemic and thrombolytic activities of H. odorata leaf extracts as new therapeutic prospects predicting the activity of some of the isolated compounds of this plant. METHODS Leaves of Hopea odorata was extracted with pu...

The participation of renal metallothionein (MT) in the toxicity and antitumor activity of cis-diamminedichloroplatinum(II) (cis-DDP) in male mice was examined. Preinduction of MT in the kidney by the s.c. administration of bismuth compounds decreased the lethality and renal and gastrointestinal toxicity caused by a single s.c. injection of cis-DDP. In the present study a correlation between the...